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Yohimbic acid

Name: Yohimbic acid
Brand: TargetMol
SKU: TN2323
Price: 97 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2323Cas No. 522-87-2

Yohimbic acid is a natural derivative of Yohimbine exhibiting weak inhibition of topoisomerase 1/2 at the μM level.

Yohimbic acid

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Purity: 99.98%

Catalog No. TN2323Cas No. 522-87-2

Yohimbic acid is a natural derivative of Yohimbine exhibiting weak inhibition of topoisomerase 1/2 at the μM level.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$97	-	In Stock
5 mg	$239	-	In Stock
10 mg	$383	-	In Stock
25 mg	$629	-	In Stock
50 mg	$889	-	In Stock
100 mg	$1,190	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Questions

Batch Information

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Purity:99.98%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Yohimbic acid is a natural derivative of Yohimbine exhibiting weak inhibition of topoisomerase 1/2 at the μM level.

Chemical Properties

Molecular Weight	340.42
Formula	C₂₀H₂₄N₂O₃
Cas No.	522-87-2
Smiles	C(O)(=O)[C@@H]1[C@]2(C[C@]3(C4=C(C=5C(N4)=CC=CC5)CCN3C[C@@]2(CC[C@@H]1O)[H])[H])[H]
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100.00 mg/mL (293.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9375 mL	14.6877 mL	29.3755 mL	146.8774 mL
5 mM	0.5875 mL	2.9375 mL	5.8751 mL	29.3755 mL
10 mM	0.2938 mL	1.4688 mL	2.9375 mL	14.6877 mL
20 mM	0.1469 mL	0.7344 mL	1.4688 mL	7.3439 mL
50 mM	0.0588 mL	0.2938 mL	0.5875 mL	2.9375 mL
100 mM	0.0294 mL	0.1469 mL	0.2938 mL	1.4688 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc