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Nafimidone

Catalog No. T68112 CAS 64212-22-2

Nafimidone shows anticonvulsant activity in a rat model of amygdala epilepsy and can be used in the treatment of chronic intractable epilepsy.

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Nafimidone, CAS 64212-22-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 76.00
5 mg	In stock	$ 177.00
10 mg	In stock	$ 260.00
25 mg	In stock	$ 506.00
50 mg	In stock	$ 690.00
100 mg	In stock	$ 982.00
500 mg	In stock	$ 1,970.00

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Purity: 99.87%

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Description	Nafimidone shows anticonvulsant activity in a rat model of amygdala epilepsy and can be used in the treatment of chronic intractable epilepsy.
In vivo	Nafimidone (600 mg/day; 12 patients), was added during 2 weeks in the hospital. Patients were then evaluated weekly for 8 weeks. Eight patients experienced 33-98% improvement in seizure control. Nafimidone had a marked inhibitory effect on the clearance of CBZ and PHT, resulting in higher plasma levels in nine patients.[3]

Molecular Weight	236.27
Formula	C15H12N2O
CAS No.	64212-22-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Robertson DW, et al. Structure-activity relationships of (arylalkyl)imidazole anticonvulsants: comparison of the (fluorenylalkyl)imidazoles with nafimidone and denzimol. J Med Chem. 1986;29(9):1577-1586. 2. Walker KA, et al. 1-(Naphthylalkyl)-1H-imidazole derivatives, a new class of anticonvulsant agents. J Med Chem. 1981;24(1):67-74. 3. Treiman DM, et al. Efficacy of nafimidone in the treatment of intractable partial seizures: report of a two-center pilot study. Epilepsia. 1985;26(6):607-611.

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Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
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Keywords

Nafimidone 64212-22-2 inhibitor inhibit

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