(2-Hydroxyethoxy)acetic acid

Name: (2-Hydroxyethoxy)acetic acid
Brand: TargetMol
SKU: T38735
Rating: 4.5 (1 reviews)

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Catalog No. T38735Cas No. 13382-47-3

Alias β-hydroxyethoxyacetic acid, HEAA

(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the primary urinary metabolite of 1,4-dioxane, serving as a reliable and sensitive short-term biomarker in urine.

(2-Hydroxyethoxy)acetic acid

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Catalog No. T38735Alias β-hydroxyethoxyacetic acid, HEAACas No. 13382-47-3

(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the primary urinary metabolite of 1,4-dioxane, serving as a reliable and sensitive short-term biomarker in urine.

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Product Introduction

Bioactivity

Description	(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the primary urinary metabolite of 1,4-dioxane, serving as a reliable and sensitive short-term biomarker in urine.
In vitro	(2-Hydroxyethoxy)acetic acid (HEAA) exhibits a pH-dependent equilibrium with its cyclic lactone form, dioxan-2-one, maintaining a stable open-chain structure in acidic conditions[1].
In vivo	The primary metabolic route for 1,4-Dioxane involves its oxidation by cytochrome P450 monooxygenase into (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid; HEAA), which is subsequently rapidly eliminated through urinary excretion[1].
Synonyms	β-hydroxyethoxyacetic acid, HEAA

Chemical Properties

Molecular Weight	120.1
Formula	C₄H₈O₄
Cas No.	13382-47-3
Relative Density.	1.290 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

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