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(±)8(9)-DiHET

Name: (±)8(9)-DiHET
Brand: TargetMol
SKU: T37227
Rating: 4.5 (1 reviews)

Catalog No. T37227 Copy Product Info

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Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. The 8(S),9(R)-EET isomer is metabolized by platelet COX to form 8(S),9(R),11(R)-THETA, a trihydroxy fatty acid which may act as a renal vasoconstrictor.

(±)8(9)-DiHET

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Catalog No. T37227

Cas No. 192461-96-4

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Pack Size	Price	USA Stock	Global Stock
25 μg	$366	35 days	35 days
50 μg	$688	35 days	35 days
100 μg	$1,300	35 days	35 days
250 μg	$2,880	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	338.488
Formula	C₂₀H₃₄O₄
Cas No.	192461-96-4
Smiles	CCCCC\C=C/C\C=C/CC(O)C(O)C\C=C/CCCC(O)=O
Relative Density.	1.025 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH 7.2): 1 mg/mL (2.95 mM), Sonication is recommended.

Ethanol: 50 mg/mL (147.72 mM), Sonication is recommended.

DMSO: 50 mg/mL (147.72 mM), Sonication is recommended.

DMF: 50 mg/mL (147.72 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.9543 mL	14.7716 mL	29.5431 mL	147.7157 mL

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	0.5909 mL	2.9543 mL	5.9086 mL	29.5431 mL
10 mM	0.2954 mL	1.4772 mL	2.9543 mL	14.7716 mL
20 mM	0.1477 mL	0.7386 mL	1.4772 mL	7.3858 mL
50 mM	0.0591 mL	0.2954 mL	0.5909 mL	2.9543 mL
100 mM	0.0295 mL	0.1477 mL	0.2954 mL	1.4772 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

8(9)-DiHET(±)8(9)DiHET(±)8(9) DiHET