Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid . In mammals, 12(R)-HETE can be produced by 12(R)-LOs and also by CYP450 oxidation. The activity of 12(R)-HETE in mammals is predominantly proinflammatory. 12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 μg | 35 days | $ 353.00 | |
50 μg | 35 days | $ 668.00 | |
100 μg | 35 days | $ 980.00 |
Description | Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid . In mammals, 12(R)-HETE can be produced by 12(R)-LOs and also by CYP450 oxidation. The activity of 12(R)-HETE in mammals is predominantly proinflammatory. 12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits. |
Molecular Weight | 320.47 |
Formula | C20H32O3 |
CAS No. | 82337-46-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Miscible
DMSO: Miscible
PBS (pH 7.2): 0.8 mg/mL
DMF: Miscible
0.1 M Na2CO3: 2 mg/mL
You can also refer to dose conversion for different animals. More
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12(R)-HETE 82337-46-0 12(R)HETE 12HETE 12(R) HETE inhibitor inhibit