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6-Chloro-3-indolyl-β-D-Glucuronide CHA

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Catalog No. T37811Cas No. 138182-20-4
Alias 16beta-Methyl-16alpha,17alpha-epoxypregnenolone

6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) is a chromogenic substrate for β-glucuronidase and can be utilized in the histochemical analysis of β-glucuronidase activity.

6-Chloro-3-indolyl-β-D-Glucuronide CHA

6-Chloro-3-indolyl-β-D-Glucuronide CHA

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Purity: 97.62%
Catalog No. T37811Alias 16beta-Methyl-16alpha,17alpha-epoxypregnenoloneCas No. 138182-20-4
6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) is a chromogenic substrate for β-glucuronidase and can be utilized in the histochemical analysis of β-glucuronidase activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$30In StockIn Stock
25 mg$48In StockIn Stock
50 mg$68In StockIn Stock
100 mg$103In StockIn Stock
500 mg$232In StockIn Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:97.62%
Appearance:Solid
Color:Red
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) is a chromogenic substrate for β-glucuronidase and can be utilized in the histochemical analysis of β-glucuronidase activity.
Synonyms16beta-Methyl-16alpha,17alpha-epoxypregnenolone
Chemical Properties
Molecular Weight442.89
FormulaC20H27ClN2O7
Cas No.138182-20-4
SmilesNC1CCCCC1.O[C@@H]1[C@@H](O)[C@H](Oc2c[nH]c3cc(Cl)ccc23)O[C@@H]([C@H]1O)C(O)=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (124.18 mM), Sonication is recommended.
DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL (1.13 mM), Sonication is recommended.
Solution Preparation Table
DMSO:PBS (pH 7.2) (1:1)/DMSO
1mg5mg10mg50mg
1 mM2.2579 mL11.2895 mL22.5790 mL112.8948 mL
DMSO
1mg5mg10mg50mg
5 mM0.4516 mL2.2579 mL4.5158 mL22.5790 mL
10 mM0.2258 mL1.1289 mL2.2579 mL11.2895 mL
20 mM0.1129 mL0.5645 mL1.1289 mL5.6447 mL
50 mM0.0452 mL0.2258 mL0.4516 mL2.2579 mL
100 mM0.0226 mL0.1129 mL0.2258 mL1.1289 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

β-glucuronidasecyclohexylammonium6Chloro3indolylβDGlucuronide (cyclohexylammonium salt)6-Chloro-3-indolyl-β-D-Glucuronide6-Chloro-3-indolyl-beta-D-Glucuronide6-Chloro-3-indolyl-b-D-Glucuronide6 Chloro 3 indolyl β D Glucuronide (cyclohexylammonium salt)
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