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Sodium carbonate

Name: Sodium carbonate
Brand: TargetMol
SKU: T22426
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22426Cas No. 497-19-8

Alias Soda Ash, Disodium carbonate, Carbonic acid disodium salt

Sodium carbonate (Soda Ash) , is the disodium salt of carbonic acid with alkalinizing property.

Sodium carbonate

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Catalog No. T22426Alias Soda Ash, Disodium carbonate, Carbonic acid disodium saltCas No. 497-19-8

Sodium carbonate (Soda Ash) , is the disodium salt of carbonic acid with alkalinizing property.

Pack Size	Price	USA Warehouse	Global Warehouse
5 g	$48	-	In Stock
10 g	$68	-	In Stock
25 g	$113	-	In Stock
50 g	$166	-	In Stock
100 g	$245	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Appearance:solid

Color:White

Resource Download

COA

Product Introduction

Sodium carbonate AI Summary

Sodium carbonate exhibits significant inhibitory activity against a broad spectrum of carbonic anhydrase (CA) enzymes from various species, including human CA isozymes and enzymes from pathogenic bacteria and fungi. Specifically, it shows moderate inhibition of human CA I and CA IV with Ki values of 15,000,000 nM and 5,700,000 nM, respectively, and weaker inhibition against human CA II and CA V with Ki values of 73,000,000 nM and 95,000,000 nM. It also inhibits recombinant beta-carbonic anhydrase from Streptococcus pneumoniae with a Ki value of 530,000 nM and alpha-carbonic anhydrase from Leptonychotes weddellii with a Ki value of 60,000 nM. Additionally, Sodium carbonate demonstrates bioactivity against human pathogens, showing inhibition of CA enzymes from organisms such as Helicobacter pylori, Sulfurihydrogenibium yellowstonense, Plasmodium falciparum, and Burkholderia pseudomallei. The compound also exhibits antifungal properties, inhibiting the growth of species like Fusarium verticillioides and Lasiodiplodia theobromae in vitro. Overall, these inhibitory effects, as evidenced by varying Ki values in the nanomolar range, suggest Sodium carbonate's potential utility in modulating CA-related physiological and pathological processes..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Sodium carbonate (Soda Ash) , is the disodium salt of carbonic acid with alkalinizing property.
Synonyms	Soda Ash, Disodium carbonate, Carbonic acid disodium salt

Chemical Properties

Molecular Weight	105.99
Formula	CNa₂O₃
Cas No.	497-19-8
Smiles	O=C([O-])[O-].[Na+].[Na+]
Relative Density.	2.53 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 20 mg/mL (188.7 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	9.4349 mL	47.1743 mL	94.3485 mL	471.7426 mL
5 mM	1.8870 mL	9.4349 mL	18.8697 mL	94.3485 mL
10 mM	0.9435 mL	4.7174 mL	9.4349 mL	47.1743 mL
20 mM	0.4717 mL	2.3587 mL	4.7174 mL	23.5871 mL
50 mM	0.1887 mL	0.9435 mL	1.8870 mL	9.4349 mL
100 mM	0.0943 mL	0.4717 mL	0.9435 mL	4.7174 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc