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7-Hydroxyisoflavone

🥰Excellent
Catalog No. T8180Cas No. 13057-72-2

7-Hydroxyisoflavone against Enterovirus 71 in vitro.

7-Hydroxyisoflavone

7-Hydroxyisoflavone

🥰Excellent
Purity: 99.88%
Catalog No. T8180Cas No. 13057-72-2
7-Hydroxyisoflavone against Enterovirus 71 in vitro.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$31In StockIn Stock
25 mg$48In StockIn Stock
50 mg$70In StockIn Stock
100 mg$98In StockIn Stock
200 mg$142In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.88%
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Product Introduction

Bioactivity
Description
7-Hydroxyisoflavone against Enterovirus 71 in vitro.
In vitro
7-hydroxyisoflavone was active against EV71.?7-Hydroxyisoflavone exhibited strong antiviral activity against three different EV71 strains.?The 50% inhibitory concentration range was between 3.25 and 4.92 μM by cytopathic effect assay.?7-Hydroxyisoflavone could reduce EV71 viral RNA and protein synthesis in a dose-dependent manner.?Time course study showed that treatment of Vero cells with 7-hydroxyisoflavone at indicated times after EV71 inoculation (0-6 h) resulted in significant antiviral activity[1].
Chemical Properties
Molecular Weight238.24
FormulaC15H10O3
Cas No.13057-72-2
SmilesOc1ccc2c(c1)occ(-c1ccccc1)c2=O
Relative Density.1.340 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 25 mg/mL (104.94 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1974 mL20.9872 mL41.9745 mL209.8724 mL
5 mM0.8395 mL4.1974 mL8.3949 mL41.9745 mL
10 mM0.4197 mL2.0987 mL4.1974 mL20.9872 mL
20 mM0.2099 mL1.0494 mL2.0987 mL10.4936 mL
50 mM0.0839 mL0.4197 mL0.8395 mL4.1974 mL
100 mM0.0420 mL0.2099 mL0.4197 mL2.0987 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

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