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7-Hydroxyisoflavone

Name: 7-Hydroxyisoflavone
Brand: TargetMol
SKU: T8180
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8180Cas No. 13057-72-2

7-Hydroxyisoflavone against Enterovirus 71 in vitro.

7-Hydroxyisoflavone

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Purity: 99.88%

Catalog No. T8180Cas No. 13057-72-2

7-Hydroxyisoflavone against Enterovirus 71 in vitro.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$31	In Stock	In Stock
25 mg	$48	In Stock	In Stock
50 mg	$70	In Stock	In Stock
100 mg	$98	In Stock	In Stock
200 mg	$142	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.88%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

7-Hydroxyisoflavone against Enterovirus 71 in vitro.

In vitro

7-hydroxyisoflavone was active against EV71.?7-Hydroxyisoflavone exhibited strong antiviral activity against three different EV71 strains.?The 50% inhibitory concentration range was between 3.25 and 4.92 μM by cytopathic effect assay.?7-Hydroxyisoflavone could reduce EV71 viral RNA and protein synthesis in a dose-dependent manner.?Time course study showed that treatment of Vero cells with 7-hydroxyisoflavone at indicated times after EV71 inoculation (0-6 h) resulted in significant antiviral activity[1].

Chemical Properties

Molecular Weight	238.24
Formula	C₁₅H₁₀O₃
Cas No.	13057-72-2
Smiles	Oc1ccc2c(c1)occ(-c1ccccc1)c2=O
Relative Density.	1.340 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (104.94 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.1974 mL	20.9872 mL	41.9745 mL	209.8724 mL
5 mM	0.8395 mL	4.1974 mL	8.3949 mL	41.9745 mL
10 mM	0.4197 mL	2.0987 mL	4.1974 mL	20.9872 mL
20 mM	0.2099 mL	1.0494 mL	2.0987 mL	10.4936 mL
50 mM	0.0839 mL	0.4197 mL	0.8395 mL	4.1974 mL
100 mM	0.0420 mL	0.2099 mL	0.4197 mL	2.0987 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc