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K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)

Catalog No. T36577

Synonyms: K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)

Histone H2B (108-125) is a peptide fragment of histone H2B that corresponds to amino acid residues 109-126 of the human histone H2B sequence. It contains an N-terminal biotinylated lysine followed by a tryptophan linker. Histone H2B can be modified by addition of an O-linked N-acetylglucosamine (GlcNAc) moiety to the serine residue at position 112, which promotes monoubiquitination of the lysine at position 120.1 Both of these modifications are associated with active transcription. Histone H2B also has lysine residues at positions 108, 116, and 120 that are subject to acetylation.2

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K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt) Chemical Structure

K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt), CAS N/A

Pack Size	Availability	Price/USD	Quantity
1 mg	Inquiry	$ 520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)
Molecular Weight	N/A

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 1 mg/mL

References and Literature

1. Fujiki, R., Hashiba, W., Sekine, H., et al. GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature 480(7378), 557-560 (2011). 2. Portela, A., and Esteller, M. Epigenetic modifications and human disease. Nat. Biotechnol. 28(10), 1057-1068 (2010).

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Keywords

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