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AT-1002 TFA (835872-35-0 free base)
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Catalog No. T13560L
Alias AT-1002 TFA
AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.
AT-1002 TFA (835872-35-0 free base)
😃Good
Catalog No. T13560LAlias AT-1002 TFA
AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $223 | 2-4 weeks | 2-4 weeks | |
| 10 mg | $398 | 2-4 weeks | 2-4 weeks | |
| 50 mg | $1,190 | 2-4 weeks | 2-4 weeks | |
| 100 mg | $1,850 | 2-4 weeks | 2-4 weeks | |
| 200 mg | Inquiry | 2-4 weeks | 2-4 weeks | |
| 500 mg | Inquiry | 2-4 weeks | 2-4 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide. |
| In vitro | AT-1002 reversibly increases the paracellular transport of molecules across the epithelial barrier. AT-1002 can undergo Cys-Cys dimerization [1]. Undifferentiated Caco-2 cells are treated with AT-1002 (0 to 5 mg/mL, 3 or 24 hours) and viability is assessed by measuring cellular ATP content. Treatment with AT-1002 for up to 3 h does not affect cell viability at any concentration. In particular, the viability of Caco-2 cells is not affected by 5 mg/mL AT-1002. AT-1002 reduces cell viability after 24 h at concentrations of 2.5 mg/mL and higher. However, the cells remain viable after 24 h if the cells are washed after exposure to AT-1002 for 3 h [2]. |
| Synonyms | AT-1002 TFA |
| Molecular Weight | 821.91 |
| Formula | C34H54F3N9O9S |
| Smiles | N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CS)C(N[C@@H]([C@H](CC)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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