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Escin IIA

🥰Excellent
Catalog No. TN1358Cas No. 158732-55-9
Alias Aescin IIA

Escin IIA, a naturally derived saponin isolated from the seeds of horse chestnut (Aesculus hippocastanum L.), has been shown to exert beneficial effects in acute inflammatory conditions in animal models. Escin IIA additionally demonstrates gastroprotective effects by reducing ethanol-induced gastric mucosal lesions in rats, thereby supporting its role in the study of anti-inflammatory and gastroprotective mechanisms in preclinical research.

Escin IIA

Escin IIA

🥰Excellent
Catalog No. TN1358Alias Aescin IIACas No. 158732-55-9
Escin IIA, a naturally derived saponin isolated from the seeds of horse chestnut (Aesculus hippocastanum L.), has been shown to exert beneficial effects in acute inflammatory conditions in animal models. Escin IIA additionally demonstrates gastroprotective effects by reducing ethanol-induced gastric mucosal lesions in rats, thereby supporting its role in the study of anti-inflammatory and gastroprotective mechanisms in preclinical research.
Pack SizePriceAvailabilityQuantity
1 mg$83In Stock
5 mg$197In Stock
10 mg$290In Stock
25 mg$489In Stock
50 mg$713In Stock
100 mg$987In Stock
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Product Introduction

Bioactivity
Description
Escin IIA, a naturally derived saponin isolated from the seeds of horse chestnut (Aesculus hippocastanum L.), has been shown to exert beneficial effects in acute inflammatory conditions in animal models. Escin IIA additionally demonstrates gastroprotective effects by reducing ethanol-induced gastric mucosal lesions in rats, thereby supporting its role in the study of anti-inflammatory and gastroprotective mechanisms in preclinical research.
In vivo
Escin IIA (10-50 mg/kg, p.o.) can effectively inhibit ethanol-induced gastric mucosal injury in rats. [1]
SynonymsAescin IIA
Chemical Properties
Molecular Weight1101.24
FormulaC54H84O23
Cas No.158732-55-9
Relative Density.1.45 g/cm3 at 20℃
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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