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4-methyl-2-Oxovalerate sodium salt

Name: 4-methyl-2-Oxovalerate sodium salt
Brand: TargetMol
SKU: T35727
Rating: 4.5 (1 reviews)

(Synonyms: Sodium α-ketoisocaproate, Sodium 4-methyl-2-oxopentanoate, 2-Ketoisocaproic acid sodium salt) Copy Product Info

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Synonyms: Sodium α-ketoisocaproate, Sodium 4-methyl-2-oxopentanoate, 2-Ketoisocaproic acid sodium salt

Catalog No. T35727 Copy Product Info

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4-methyl-2-Oxovalerate sodium salt is a product generated from leucine catalyzed by transaminase and promotes insulin secretion. It can be oxidatively degraded into acetyl-CoA and acetoacetic acid, or regenerate leucine via transamination with glutamate while producing α-ketoglutarate.

Cas No. 4502-00-5

Pack Size	Price	USA Stock	Global Stock	Quantity
1 g	$79	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	4-methyl-2-Oxovalerate sodium salt is a product generated from leucine catalyzed by transaminase and promotes insulin secretion. It can be oxidatively degraded into acetyl-CoA and acetoacetic acid, or regenerate leucine via transamination with glutamate while producing α-ketoglutarate.
Synonyms	Sodium α-ketoisocaproate, Sodium 4-methyl-2-oxopentanoate, 2-Ketoisocaproic acid sodium salt

Chemical Properties

Molecular Weight	152.12
Formula	C₆H₉NaO₃
Cas No.	4502-00-5
Smiles	O=C(C(CC(C)C)=O)[O-].[Na+]

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH 7.2): 10 mg/mL (65.74 mM), Sonication is recommended.

Ethanol: 5 mg/mL (32.87 mM), Sonication is recommended.

H2O: 40 mg/mL (262.95 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/PBS (pH 7.2)/H2O

	1mg	5mg	10mg	50mg
1 mM	6.5738 mL	32.8688 mL	65.7376 mL	328.6879 mL
5 mM	1.3148 mL	6.5738 mL	13.1475 mL	65.7376 mL
10 mM	0.6574 mL	3.2869 mL	6.5738 mL	32.8688 mL
20 mM	0.3287 mL	1.6434 mL	3.2869 mL	16.4344 mL

PBS (pH 7.2)/H2O

	1mg	5mg	10mg	50mg
50 mM	0.1315 mL	0.6574 mL	1.3148 mL	6.5738 mL

H2O

	1mg	5mg	10mg	50mg
100 mM	0.0657 mL	0.3287 mL	0.6574 mL	3.2869 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Keywords

4methyl2Oxovalerate (sodium salt)4-methyl-2-Oxovalerate4 methyl 2 Oxovalerate (sodium salt)

Related Tags: 4-methyl-2-Oxovalerate sodium salt chemical structure | 4-methyl-2-Oxovalerate sodium salt formula | 4-methyl-2-Oxovalerate sodium salt molecular weight