Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methylnaltrexone iodide, a quaternary derivative of Naltrexone, is an orally active and selective antagonist of the mu-opioid receptor. It acts peripherally in the gastrointestinal tract to antagonize the receptor. Furthermore, Methylnaltrexone iodide exhibits limited permeability across the blood-brain barrier.
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5 mg | Inquiry | $ 970.00 |
Description | Methylnaltrexone iodide, a quaternary derivative of Naltrexone, is an orally active and selective antagonist of the mu-opioid receptor. It acts peripherally in the gastrointestinal tract to antagonize the receptor. Furthermore, Methylnaltrexone iodide exhibits limited permeability across the blood-brain barrier. |
In vivo | At a dosage of 2.0 mg/kg, Methylnaltrexone iodide, when injected into morphine-induced male Albino Hartley strain guinea pigs, effectively returned the number of coughs to baseline levels without affecting nociception [2]. |
Synonyms | Naltrexonium methiodide |
Molecular Weight | 483.346 |
Formula | C21H26INO4 |
CAS No. | 73232-53-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Methylnaltrexone iodide 73232-53-8 Methylnaltrexone Iodide Naltrexonium methiodide inhibitor inhibit