Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 473.00 | |
1 mg | 35 days | $ 898.00 |
Description | (3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner. |
Molecular Weight | 340.42 |
Formula | C20H24N2O3 |
CAS No. | 53467-23-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methanol: Soluble
You can also refer to dose conversion for different animals. More
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(3S)-hydroxy Quinidine 53467-23-5 (3S) hydroxy Quinidine (3S)hydroxy Quinidine hydroxy Quinidine inhibitor inhibit