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Glucosamine 6-sulfate

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Catalog No. T37598Cas No. 91674-26-9
Alias GlcN6S, D-Glucosamine-6-sulfate

Glucosamine 6-sulfate (GlcN6S) is a glucosamine derivative exhibiting anti-inflammatory effects in experimental autoimmune encephalomyelitis (EAE). It inhibits gene expression of IL-12, T-bet, and IFN-γ, suppresses Th1 CD4 T cell differentiation, and may be utilised in multiple sclerosis (MS) research.

Glucosamine 6-sulfate
Other Forms of Glucosamine 6-sulfate:

Glucosamine 6-sulfate

🥰Excellent
Catalog No. T37598Alias GlcN6S, D-Glucosamine-6-sulfateCas No. 91674-26-9
Glucosamine 6-sulfate (GlcN6S) is a glucosamine derivative exhibiting anti-inflammatory effects in experimental autoimmune encephalomyelitis (EAE). It inhibits gene expression of IL-12, T-bet, and IFN-γ, suppresses Th1 CD4 T cell differentiation, and may be utilised in multiple sclerosis (MS) research.
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5 mg$31In Stock
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Product Introduction

Bioactivity
Description
Glucosamine 6-sulfate (GlcN6S) is a glucosamine derivative exhibiting anti-inflammatory effects in experimental autoimmune encephalomyelitis (EAE). It inhibits gene expression of IL-12, T-bet, and IFN-γ, suppresses Th1 CD4 T cell differentiation, and may be utilised in multiple sclerosis (MS) research.
SynonymsGlcN6S, D-Glucosamine-6-sulfate
Chemical Properties
Molecular Weight259.23
FormulaC6H13NO8S
Cas No.91674-26-9
Smiles[C@H]([C@@H]([C@H](C=O)N)O)([C@@H](COS(=O)(=O)O)O)O
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
PBS (pH 7.2): 5 mg/mL (19.29 mM), Sonication is recommended.
H2O: 200 mg/mL (771.52 mM)
DMF: 0.5 mg/mL (1.93 mM), Sonication is recommended.
DMSO: 2 mg/mL (7.72 mM), Sonication is recommended.
Solution Preparation Table
DMF/DMSO/PBS (pH 7.2)/H2O
1mg5mg10mg50mg
1 mM3.8576 mL19.2879 mL38.5758 mL192.8789 mL
DMSO/PBS (pH 7.2)/H2O
1mg5mg10mg50mg
5 mM0.7715 mL3.8576 mL7.7152 mL38.5758 mL
PBS (pH 7.2)/H2O
1mg5mg10mg50mg
10 mM0.3858 mL1.9288 mL3.8576 mL19.2879 mL
H2O
1mg5mg10mg50mg
20 mM0.1929 mL0.9644 mL1.9288 mL9.6439 mL
50 mM0.0772 mL0.3858 mL0.7715 mL3.8576 mL
100 mM0.0386 mL0.1929 mL0.3858 mL1.9288 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

DGlucosamine6sulfateD Glucosamine 6 sulfate
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