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Glucosamine 6-sulfate (Synonyms: GlcN6S, D-Glucosamine-6-sulfate)

Name: Glucosamine 6-sulfate
Brand: TargetMol
SKU: T37598
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T37598 Copy Product Info

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Glucosamine 6-sulfate (GlcN6S) is a glucosamine derivative exhibiting anti-inflammatory effects in experimental autoimmune encephalomyelitis (EAE). It inhibits gene expression of IL-12, T-bet, and IFN-γ, suppresses Th1 CD4 T cell differentiation, and may be utilised in multiple sclerosis (MS) research.

Glucosamine 6-sulfate

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Catalog No. T37598

Synonyms GlcN6S, D-Glucosamine-6-sulfate

Cas No. 91674-26-9

Pack Size	Price	USA Stock	Global Stock	Quantity
5 mg	$31	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:Yellow

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Product Introduction

Bioactivity

Description	Glucosamine 6-sulfate (GlcN6S) is a glucosamine derivative exhibiting anti-inflammatory effects in experimental autoimmune encephalomyelitis (EAE). It inhibits gene expression of IL-12, T-bet, and IFN-γ, suppresses Th1 CD4 T cell differentiation, and may be utilised in multiple sclerosis (MS) research.
Synonyms	GlcN6S, D-Glucosamine-6-sulfate

Chemical Properties

Molecular Weight	259.23
Formula	C₆H₁₃NO₈S
Cas No.	91674-26-9
Smiles	[C@H]([C@@H]([C@H](C=O)N)O)([C@@H](COS(=O)(=O)O)O)O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

PBS (pH 7.2): 5 mg/mL (19.29 mM), Sonication is recommended.

H2O: 200 mg/mL (771.52 mM)

DMF: 0.5 mg/mL (1.93 mM), Sonication is recommended.

DMSO: 2 mg/mL (7.72 mM), Sonication is recommended.

Solution Preparation Table

DMF/DMSO/PBS (pH 7.2)/H2O

	1mg	5mg	10mg	50mg
1 mM	3.8576 mL	19.2879 mL	38.5758 mL	192.8789 mL

DMSO/PBS (pH 7.2)/H2O

	1mg	5mg	10mg	50mg
5 mM	0.7715 mL	3.8576 mL	7.7152 mL	38.5758 mL

PBS (pH 7.2)/H2O

	1mg	5mg	10mg	50mg
10 mM	0.3858 mL	1.9288 mL	3.8576 mL	19.2879 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.1929 mL	0.9644 mL	1.9288 mL	9.6439 mL
50 mM	0.0772 mL	0.3858 mL	0.7715 mL	3.8576 mL
100 mM	0.0386 mL	0.1929 mL	0.3858 mL	1.9288 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc