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Glucosamine 6-sulfate

Name: Glucosamine 6-sulfate
Brand: TargetMol
SKU: T37598
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T37598Cas No. 91674-26-9

Alias GlcN6S, D-Glucosamine-6-sulfate

Glucosamine 6-sulfate (GlcN6S) is a glucosamine derivative exhibiting anti-inflammatory effects in experimental autoimmune encephalomyelitis (EAE). It inhibits gene expression of IL-12, T-bet, and IFN-γ, suppresses Th1 CD4 T cell differentiation, and may be utilised in multiple sclerosis (MS) research.

Glucosamine 6-sulfate

🥰Excellent

Catalog No. T37598Alias GlcN6S, D-Glucosamine-6-sulfateCas No. 91674-26-9

Pack Size	Price	Availability	Quantity
1 mg	$30	In Stock
5 mg	$57	In Stock

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Product Introduction

Bioactivity

Description	Glucosamine 6-sulfate (GlcN6S) is a glucosamine derivative exhibiting anti-inflammatory effects in experimental autoimmune encephalomyelitis (EAE). It inhibits gene expression of IL-12, T-bet, and IFN-γ, suppresses Th1 CD4 T cell differentiation, and may be utilised in multiple sclerosis (MS) research.
Synonyms	GlcN6S, D-Glucosamine-6-sulfate

Chemical Properties

Molecular Weight	259.23
Formula	C₆H₁₃NO₈S
Cas No.	91674-26-9
Smiles	[C@H]([C@@H]([C@H](C=O)N)O)([C@@H](COS(=O)(=O)O)O)O
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

PBS (pH 7.2): 5 mg/mL (19.29 mM), Sonication is recommended.

H2O: 200 mg/mL (771.52 mM)

DMF: 0.5 mg/mL (1.93 mM), Sonication is recommended.

DMSO: 2 mg/mL (7.72 mM), Sonication is recommended.

Solution Preparation Table

DMF/DMSO/PBS (pH 7.2)/H2O

	1mg	5mg	10mg	50mg
1 mM	3.8576 mL	19.2879 mL	38.5758 mL	192.8789 mL

DMSO/PBS (pH 7.2)/H2O

	1mg	5mg	10mg	50mg
5 mM	0.7715 mL	3.8576 mL	7.7152 mL	38.5758 mL

PBS (pH 7.2)/H2O

	1mg	5mg	10mg	50mg
10 mM	0.3858 mL	1.9288 mL	3.8576 mL	19.2879 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.1929 mL	0.9644 mL	1.9288 mL	9.6439 mL
50 mM	0.0772 mL	0.3858 mL	0.7715 mL	3.8576 mL
100 mM	0.0386 mL	0.1929 mL	0.3858 mL	1.9288 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc