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Lolitrem B

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Catalog No. T32851Cas No. 81771-19-9

Lolitrem B is one of many toxins produced by a fungus called Epichloë festucae (var. lolii), which grows in perennial ryegrass. The fungus is symbiotic with the ryegrass; it doesn't harm the plant, and the toxins it produces kill insects that feed on ryegrass. Lolitrem B is one of these toxins, but it is also harmful to mammals.

Lolitrem B

Lolitrem B

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😃Good
Catalog No. T32851Cas No. 81771-19-9
Lolitrem B is one of many toxins produced by a fungus called Epichloë festucae (var. lolii), which grows in perennial ryegrass. The fungus is symbiotic with the ryegrass; it doesn't harm the plant, and the toxins it produces kill insects that feed on ryegrass. Lolitrem B is one of these toxins, but it is also harmful to mammals.
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25 mg$1,520InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Lolitrem B is one of many toxins produced by a fungus called Epichloë festucae (var. lolii), which grows in perennial ryegrass. The fungus is symbiotic with the ryegrass; it doesn't harm the plant, and the toxins it produces kill insects that feed on ryegrass. Lolitrem B is one of these toxins, but it is also harmful to mammals.
Chemical Properties
Molecular Weight685.902
FormulaC42H55NO7
Cas No.81771-19-9
Smiles[H][C@]12O[C@@]11[C@]([H])(CC[C@]3(C)[C@@]4(C)c5[nH]c6ccc7C(=O)[C@]8([H])[C@@]([H])(Cc7c6c5C[C@]4([H])CC[C@@]13O)C(C)(C)OC8(C)C)O[C@@]1([H])[C@@]2([H])O[C@@H](OC1(C)C)C=C(C)C |wU:8.9,29.34,22.23,45.54,1.0,wD:33.40,3.2,10.11,20.21,4.5,48.62,43.51,(2.73,.99,;3.02,2.5,;4.54,2.21,;4.03,3.66,;3.53,5.12,;3.02,6.57,;4.54,6.28,;6.05,5.99,;6.55,4.54,;7.56,5.7,;8.06,4.25,;8.2,5.78,;9.29,5.18,;9.74,6.65,;11.28,6.68,;12.29,7.85,;13.8,7.56,;14.3,6.1,;15.82,5.81,;16.82,6.98,;16.32,4.36,;17.44,5.41,;15.31,3.19,;14.43,1.93,;13.8,3.48,;13.3,4.94,;11.78,5.23,;10.56,4.3,;10.11,2.82,;8.57,2.79,;9.22,1.4,;7.56,1.63,;6.05,1.92,;5.54,3.37,;5.41,1.84,;16.11,1.87,;16.28,.34,;14.89,.93,;17.61,2.22,;17.74,3.76,;18.19,5.23,;19.25,3.47,;2.02,5.41,;1.01,4.24,;.5,5.7,;1.51,2.79,;2.02,1.33,;.5,1.63,;-1.01,1.92,;-1.51,3.37,;-.5,4.53,;.04,5.97,;-1.83,5.33,;-2.02,.75,;-3.53,1.04,;-4.54,-.12,;-4.03,2.5,)|
Relative Density.1.30 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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