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N-Acetyldemecolcine

Name: N-Acetyldemecolcine
Brand: TargetMol
SKU: TN7063
Price: 467 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN7063Cas No. 7336-40-5

Alias NSC 403155, N-Methylcolchicine, N-Acetyldemecolcine

N-Acetyldemecolcine (N-Methylcolchicine) is a methylated form of Colchicine.

N-Acetyldemecolcine

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Purity: 99.47%

Catalog No. TN7063Alias NSC 403155, N-Methylcolchicine, N-AcetyldemecolcineCas No. 7336-40-5

N-Acetyldemecolcine (N-Methylcolchicine) is a methylated form of Colchicine.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$77	-	In Stock
5 mg	$192	-	In Stock
10 mg	$285	-	In Stock
25 mg	$467	-	In Stock
50 mg	Preferential	-	In Stock
1 mL x 10 mM (in DMSO)	$294	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.47%

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description	N-Acetyldemecolcine (N-Methylcolchicine) is a methylated form of Colchicine.
Synonyms	NSC 403155, N-Methylcolchicine, N-Acetyldemecolcine

Chemical Properties

Molecular Weight	413.46
Formula	C₂₃H₂₇NO₆
Cas No.	7336-40-5
Smiles	O(C)C1=C2C=3C([C@@H](N(C(C)=O)C)CCC2=CC(OC)=C1OC)=CC(=O)C(OC)=CC3
Relative Density.	1.24g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (157.21 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4186 mL	12.0931 mL	24.1861 mL	120.9307 mL
5 mM	0.4837 mL	2.4186 mL	4.8372 mL	24.1861 mL
10 mM	0.2419 mL	1.2093 mL	2.4186 mL	12.0931 mL
20 mM	0.1209 mL	0.6047 mL	1.2093 mL	6.0465 mL
50 mM	0.0484 mL	0.2419 mL	0.4837 mL	2.4186 mL
100 mM	0.0242 mL	0.1209 mL	0.2419 mL	1.2093 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc