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ICI 215,001 hydrochloride

Name: ICI 215,001 hydrochloride
Brand: TargetMol
SKU: T36928
Rating: 4.5 (1 reviews)

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Catalog No. T36928Cas No. 141269-99-0

ICI 215,001 hydrochloride acts as an antagonist at β1 and β2 adrenergic receptors when it has low intrinsic agonist activity.

ICI 215,001 hydrochloride

😃Good

Catalog No. T36928Cas No. 141269-99-0

ICI 215,001 hydrochloride acts as an antagonist at β1 and β2 adrenergic receptors when it has low intrinsic agonist activity.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
50 mg	$434	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description

ICI 215,001 hydrochloride acts as an antagonist at β1 and β2 adrenergic receptors when it has low intrinsic agonist activity.

Chemical Properties

Molecular Weight	361.39
Formula	C₁₉H₂₃NO₆
Cas No.	141269-99-0
Smiles	O(CCNC[C@@H](COC1=CC=CC=C1)O)C2=CC=C(OCC(O)=O)C=C2
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: > 10 mM, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7671 mL	13.8355 mL	27.6709 mL	138.3547 mL
5 mM	0.5534 mL	2.7671 mL	5.5342 mL	27.6709 mL
10 mM	0.2767 mL	1.3835 mL	2.7671 mL	13.8355 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ICI 215,001 Hydrochloride