potent — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T35862	Cucurbit[8]uril		Others
	Cucurbit[8]uril is a highly effective and safe supramolecular compound that promotes protein heterodimerization. It selectively induces the heterodimerization of methylviologen and naphthalene functionalized proteins, de...		Others
T9223	RO-0335		Reverse Transcriptase
	RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical is...		Reverse Transcriptase
T9215	ELOVL6-IN-2		Others
	ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.		Others
T9194	UMB298		Epigenetic Reader Domain
	UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM.		Epigenetic Reader Domain
T9214	ELOVL6-IN-1		Others
	ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner...		Others
T9202	DDO-5936		HSP
	DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.		HSP
T9164	BMS-986242	BMS986242	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T25492	Hepln-13	Hepln 13,Hepln13	c-Met/HGFR
	Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.		c-Met/HGFR
T9541	CTB	Cholera Toxin B subunit	Epigenetic Reader Domain
	CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.		Epigenetic Reader Domain
T10525	SCD1 inhibitor-4		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T6977	SB-366791	SB366791	TRP/TRPV Channel
	SB-366791 is a new and selective cinnamide TRPV1 antagonist.		TRP/TRPV Channel
T15032	CYM50308		S1P Receptor , LPL Receptor
	CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM). CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM and it shows 37-fold more sel...		S1P Receptor , LPL Receptor
T36670	JNJ-67856633		MALT
	JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease . JNJ-67856633 lead to tumor stasis in some cases.		MALT
T26324	VU0071063	VU 0071063,VU-0071063	Potassium Channel
	VU0071063 is a Kir6.2/SUR1 activator.		Potassium Channel
T3691	(Rac)-SAR131675	SAR131675	VEGFR
	(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h...		VEGFR
T9276	SBC-115337		Others , Serine/threonin kinase
	SBC-115337 is a PCSK9 inhibitor.		Others , Serine/threonin kinase
T4697	ABBV-744	ABBV744	Epigenetic Reader Domain , HIV Protease
	ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.		Epigenetic Reader Domain , HIV Protease
T6052	GW 441756		Apoptosis , Raf , Trk receptor , CDK
	GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.		Apoptosis , Raf , Trk receptor , CDK
T28804	Slingshot inhibitor D3	JHN76359	Others
	Slingshot inhibitor D3 (JHN76359) is a potent inhibitor of the Protein Phosphatase Slingshot.		Others
T2024	A-803467	A 803467,A803467	Sodium Channel
	A-803467 is a selective NaV1.8 channel blocker.		Sodium Channel