t 3

T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite

CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.

T3-ATA S-isomer, the S-isomer of T3-ATA, represents the active form of the thyroid hormone.

T3Inh-1 is a potent and selective ppGalNAc-T3 inhibitor with IC50 of 7 µM. T3Inh-1 protects against breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in tissue cells and mice without causing any toxic side effects.

T3 Peptide is an active fragment of tumstatin. By binding to integrins αvβ3/αvβ5, it activates the PI3K/Akt/p70S6K signaling pathway, thereby promoting the proliferation and migration of rat cardiac fibroblasts.

Dextran T3 (MW 3,000) is a dehydrated glucose polymer with an average molecular weight of 3,000. It exhibits excellent biodegradability and biocompatibility, making it suitable for use in food, pharmaceuticals, cosmetics, and research applications.

T3-KLH is a hapten-carrier protein conjugate formed by coupling T3 (thyroxine) to keyhole limpet hemocyanin (KLH). As a hapten, T3 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. T3-KLH may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M PBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

T3-OVA is a hapten-carrier protein conjugate formed by coupling T3 (thyroxine) to chicken ovalbumin (OVA). As a hapten, T3 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.

T3-BSA is a hapten-carrier protein conjugate formed by coupling T3 (thyroxine) to bovine serum albumin (BSA). As a hapten, T3 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.

RORγt agonist 3 is a potent agonist of RORγt that induces Th17 cell differentiation, increases levels of pro-inflammatory cytokines, and enhances lymphocyte cytotoxicity. Moreover, [it] blocks the production of regulatory T cells and suppresses the immune response.

RORγt Inverse Agonist 3 is a potent, selective, and orally active inverse agonist of RORγ with EC50 values of 0.22 μM for hRORγ and 0.15 μM for RORγt (human IL-17 cells), respectively.

Liothyronine (Tresitope) is a synthetic and highly active thyroid hormone that acts as an effective agonist of TRα and TRβ (Ki = 2.33 nM for both hTRα and hTRβ). It activates the TRβ1 receptor, promotes the metabolism of carbohydrates, proteins, and fats, accelerates the oxidative processes in tissue cells, maintains basal metabolic rate, and supports normal growth and development. Liothyronine can be used to induce hyperthyroidism models.

Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).

Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells.

Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.

HDAC3-IN-T326 is a potent and selective HDAC3 inhibitor that acts by increasing NF-κB acetylation and activating HIV gene expression in latent HIV-infected cells.

Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine.

T3SS-1-IN-1 is an inhibitor of T3SS-1. It suppresses the secretion of SipA and the activity of HilD with IC50 values of 29.2 μM and 16.9 μM, respectively. T3SS-1-IN-1 can be utilized in studies related to combating Salmonella virulence.

T3SS-IN-5 (Compound F9) is a specific inhibitor of the type III secretion system (T3SS), a virulence factor. By suppressing the expression of genes associated with T3SS, T3SS-IN-5 reduces the pathogenicity of bacteria without affecting their viability.

Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities. It can be used to study hypothyroidism, stroke and cognitive dysfunction.

CLK-IN-T3N, the negative control of CLK-IN-T3 , is a chemical probe for CDC-like kinase (CLK) .

AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts [1] .

T3SS-IN-1 (compound B9) is a potent inhibitor of the type III secretion system (T3SS) that also suppresses hpa1 promoter activity and harpin protein expression, without impacting bacterial growth [1].

T3SS-IN-2 (Compound 2h) is an inhibitor of the type three secretion system (T3SS) used in bacterial infection research [1].