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Fructose-arginine (Alias: J1.147.777A, Fructose arginine, Arginyl-fructose, Arginyl fructose)

Name: Fructose-arginine
Brand: TargetMol
SKU: T31878
Rating: 4.5 (1 reviews)

Catalog No. T31878 Copy Product Info

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Fructose-arginine is a non-saponin molecule from Korean Red Ginseng that attenuates AIM2 inflammatory vesicle activation.

Fructose-arginine

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Catalog No. T31878

Alias J1.147.777A, Fructose arginine, Arginyl-fructose, Arginyl fructose

Fructose-arginine is a non-saponin molecule from Korean Red Ginseng that attenuates AIM2 inflammatory vesicle activation.

Cas No. 25020-14-8

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Pack Size	Price	USA Stock	Global Stock
1 mg	$293	8-10 weeks	8-10 weeks
5 mg	$722	8-10 weeks	8-10 weeks
10 mg	$987	8-10 weeks	8-10 weeks
25 mg	$1,520	8-10 weeks	8-10 weeks
50 mg	$1,980	8-10 weeks	8-10 weeks

In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Fructose-arginine is a non-saponin molecule from Korean Red Ginseng that attenuates AIM2 inflammatory vesicle activation.
In vitro	METHODS: LPS-primed BMDM or NLRP3 inflammasome were treated with increasing doses of synthetic fructose-arginine (50, 250, 500 μg/mL) during AIM2 activation. RESULTS: Fructose-arginine treatment significantly attenuated dsDNA-mediated IL-1β release resulting from AIM2 inflammasome activation, but AFG did not alter IL-1β levels. [3]
Synonyms	J1.147.777A, Fructose arginine, Arginyl-fructose, Arginyl fructose

Chemical Properties

Molecular Weight	336.34
Formula	C₁₂H₂₄N₄O₇
Cas No.	25020-14-8
Smiles	[C@H](NCC([C@H]([C@@H]([C@@H](CO)O)O)O)=O)(CCCNC(=N)N)C(O)=O
Relative Density.	1.60 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 237.5 mg/mL (706.13 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9732 mL	14.8659 mL	29.7318 mL	148.6591 mL
5 mM	0.5946 mL	2.9732 mL	5.9464 mL	29.7318 mL
10 mM	0.2973 mL	1.4866 mL	2.9732 mL	14.8659 mL
20 mM	0.1487 mL	0.7433 mL	1.4866 mL	7.4330 mL
50 mM	0.0595 mL	0.2973 mL	0.5946 mL	2.9732 mL
100 mM	0.0297 mL	0.1487 mL	0.2973 mL	1.4866 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc