Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nusinersen, an antisense oligonucleotide drug, modifies the pre-messenger RNA (pre-mRNA) splicing of the SMN2 gene, thereby enhancing the production of the full-length Survival Motor Neuron (SMN) protein.
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5 mg | Inquiry | Inquiry | |
10 mg | Inquiry | Inquiry |
Description | Nusinersen, an antisense oligonucleotide drug, modifies the pre-messenger RNA (pre-mRNA) splicing of the SMN2 gene, thereby enhancing the production of the full-length Survival Motor Neuron (SMN) protein. |
In vitro | Nusinersen, an SMN-ASO, enhances SMN levels by inhibiting an intronic splice silencer within SMN2. This action promotes the inclusion of exon 7, leading to the production of full-length SMN2 transcripts[2]. |
Molecular Weight | N/A |
CAS No. | 1258984-36-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Nusinersen 1258984-36-9 inhibitor inhibit