Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DiABZI-C2-NH2, a STING agonist with a primary amine functionality, is an active analogue.
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5 mg | Inquiry | $ 648.00 | |
10 mg | Inquiry | $ 997.00 |
Description | DiABZI-C2-NH2, a STING agonist with a primary amine functionality, is an active analogue. |
In vitro | The author devised a strategy to combine two ABZI-based compounds, creating linked ABZIs (diABZIs) that show improved interaction with STING and enhanced cellular activity. When administered intravenously, a diABZI STING agonist significantly inhibited tumor growth in mice with syngeneic colon cancers, achieving complete and enduring tumor regression. Additionally, diABZI-C2-NH2 was covalently bound to sepharose beads to isolate target proteins from THP1 cell lysate for further study. |
Synonyms | diABZI-C2-NH2 |
Molecular Weight | 721.827 |
Formula | C36H43N13O4 |
CAS No. | 2137975-93-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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diABZI-C2-NH2 2137975-93-8 diABZI-C-2-NH2 diABZI C2 NH2 diABZIC2NH2 inhibitor inhibit