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Tos-O-C4-NH-Boc

Name: Tos-O-C4-NH-Boc
Brand: TargetMol
SKU: T39235
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T39235Cas No. 180851-50-7

Tos-O-C4-NH-Boc is an alkyl ether-type PROTAC linker, used for synthesizing PROTAC molecules.

Tos-O-C4-NH-Boc

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Purity: 99.37%

Catalog No. T39235Cas No. 180851-50-7

Tos-O-C4-NH-Boc is an alkyl ether-type PROTAC linker, used for synthesizing PROTAC molecules.

Pack Size	Price	Availability	Quantity
200 mg	$29	In Stock

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Batch Information

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Purity:99.37%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

Tos-O-C4-NH-Boc is an alkyl ether-type PROTAC linker, used for synthesizing PROTAC molecules.

Chemical Properties

Molecular Weight	343.44
Formula	C₁₆H₂₅NO₅S
Cas No.	180851-50-7
Smiles	O=C(OC(C)(C)C)NCCCCOS(=O)(=O)C1=CC=C(C=C1)C

Storage & Solubility Information

Storage

keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (232.94 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9117 mL	14.5586 mL	29.1172 mL	145.5858 mL
5 mM	0.5823 mL	2.9117 mL	5.8234 mL	29.1172 mL
10 mM	0.2912 mL	1.4559 mL	2.9117 mL	14.5586 mL
20 mM	0.1456 mL	0.7279 mL	1.4559 mL	7.2793 mL
50 mM	0.0582 mL	0.2912 mL	0.5823 mL	2.9117 mL
100 mM	0.0291 mL	0.1456 mL	0.2912 mL	1.4559 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc