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Tos-O-C4-NH-Boc

🥰Excellent
Catalog No. T39235Cas No. 180851-50-7

Tos-O-C4-NH-Boc is an alkyl ether-type PROTAC linker, used for synthesizing PROTAC molecules.

Tos-O-C4-NH-Boc

Tos-O-C4-NH-Boc

🥰Excellent
Purity: 99.37%
Catalog No. T39235Cas No. 180851-50-7
Tos-O-C4-NH-Boc is an alkyl ether-type PROTAC linker, used for synthesizing PROTAC molecules.
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200 mg$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.37%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Tos-O-C4-NH-Boc is an alkyl ether-type PROTAC linker, used for synthesizing PROTAC molecules.
Chemical Properties
Molecular Weight343.44
FormulaC16H25NO5S
Cas No.180851-50-7
SmilesO=C(OC(C)(C)C)NCCCCOS(=O)(=O)C1=CC=C(C=C1)C
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (232.94 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (9.61 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9117 mL14.5586 mL29.1172 mL145.5858 mL
5 mM0.5823 mL2.9117 mL5.8234 mL29.1172 mL
10 mM0.2912 mL1.4559 mL2.9117 mL14.5586 mL
20 mM0.1456 mL0.7279 mL1.4559 mL7.2793 mL
50 mM0.0582 mL0.2912 mL0.5823 mL2.9117 mL
100 mM0.0291 mL0.1456 mL0.2912 mL1.4559 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tos-O-C4-NH-BocTos-O-C-4-NH-BocTosOC4NHBocTos O C4 NH Boc
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