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LJ-001 (Alias: LJ001, LJ 001)

Catalog No. T32804 Copy Product Info
Purity: 99.34%
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LJ-001 shows broad-spectrum activity against virtually all enveloped RNA and DNA viruses. LJ001 inhibits the infection of transmissible gastroenteritis virus (TGEV) and porcine delta coronavirus (PDCoV).

LJ-001

Copy Product Info
😃Good
Catalog No. T32804
Alias LJ001, LJ 001

LJ-001 shows broad-spectrum activity against virtually all enveloped RNA and DNA viruses. LJ001 inhibits the infection of transmissible gastroenteritis virus (TGEV) and porcine delta coronavirus (PDCoV).

LJ-001
Cas No. 851305-26-5
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$58In StockIn Stock
5 mg$139In StockIn Stock
10 mg$222In StockIn Stock
25 mg$446In StockIn Stock
50 mg$662In StockIn Stock
100 mg$928In StockIn Stock
1 mL x 10 mM (in DMSO)$153In StockIn Stock
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.34%
Appearance:Solid
Color:Red
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Product Introduction

Bioactivity
Description
LJ-001 shows broad-spectrum activity against virtually all enveloped RNA and DNA viruses. LJ001 inhibits the infection of transmissible gastroenteritis virus (TGEV) and porcine delta coronavirus (PDCoV).
In vitro
In ST cells, LJ001 (12.5 µM) decreases the N-protein expression of TGEV and PDCoV and the gene mRNA expression in a time-dependent manner. LJ001 shows activities against HIV, HCV, influenza, Ebola, poxviruses and arenaviruses[3].
In vivo
In female BALB/c mice, oral gavage and intraperitoneal administration of LJ001 (20-50 mg/kg) shows no toxicity except a slight elevation in serum cholesterol levels[4].
SynonymsLJ001, LJ 001
Chemical Properties
Molecular Weight327.42
FormulaC17H13NO2S2
Cas No.851305-26-5
SmilesC(\C=1OC(=CC1)C2=CC=CC=C2)=C\3/C(=O)N(CC=C)C(=S)S3
Relative Density.1.37 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 3.28 mg/mL (10.02 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0542 mL15.2709 mL30.5418 mL152.7091 mL
5 mM0.6108 mL3.0542 mL6.1084 mL30.5418 mL
10 mM0.3054 mL1.5271 mL3.0542 mL15.2709 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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