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(Rac)-Salvianic acid A
🥰Excellent
Catalog No. T39825Cas No. 23028-17-3
Alias (Rac)-Tanshinol, (Rac)-Danshensu
(Rac)-Salvianic acid A is the racemic form of Salvianic acid A, an orally active phenolic compound. (Rac)-Salvianic acid A activates the Nrf2/HO-1 signaling pathway while inhibiting the NF-κB pathway, exhibiting potential for antioxidant, anti-apoptotic, and anti-pulmonary inflammatory effects. (Rac)-Salvianic acid A is suitable for research in COVID-19, cardiovascular, and cerebrovascular diseases.
(Rac)-Salvianic acid A
🥰Excellent
Purity: 99.90%
Catalog No. T39825Alias (Rac)-Tanshinol, (Rac)-DanshensuCas No. 23028-17-3
(Rac)-Salvianic acid A is the racemic form of Salvianic acid A, an orally active phenolic compound. (Rac)-Salvianic acid A activates the Nrf2/HO-1 signaling pathway while inhibiting the NF-κB pathway, exhibiting potential for antioxidant, anti-apoptotic, and anti-pulmonary inflammatory effects. (Rac)-Salvianic acid A is suitable for research in COVID-19, cardiovascular, and cerebrovascular diseases.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $30 | - | In Stock | |
| 5 mg | $48 | - | In Stock | |
| 10 mg | $73 | - | In Stock | |
| 25 mg | $118 | - | In Stock | |
| 50 mg | $176 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.90%
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Product Introduction
Bioactivity
Chemical Properties
| Description | (Rac)-Salvianic acid A is the racemic form of Salvianic acid A, an orally active phenolic compound. (Rac)-Salvianic acid A activates the Nrf2/HO-1 signaling pathway while inhibiting the NF-κB pathway, exhibiting potential for antioxidant, anti-apoptotic, and anti-pulmonary inflammatory effects. (Rac)-Salvianic acid A is suitable for research in COVID-19, cardiovascular, and cerebrovascular diseases. |
| In vitro | (Rac)-Salvianic acid A (6-36 μM, 24 hours) exhibited a dose-dependent inhibitory effect on LPS-induced decrease in vascular endothelial cell activity [2]. (Rac)-Salvianic acid A (10 or 20 μM, 24 hours) could inhibit lipopolysaccharide (HY-D1056)-induced apoptosis of vascular endothelial cells, and its mechanism of action was achieved by regulating glutathione peroxidase activity and malondialdehyde levels [2]. |
| In vivo | In a high-fat diet-induced atherosclerosis (AS) rat model, (Rac)-Salvianic acid A (3 mg/kg or 10 mg/kg, orally administered once daily for 6 consecutive weeks) inhibited inflammatory responses and oxidative stress, demonstrating protective effects against atherosclerosis [1]. |
| Synonyms | (Rac)-Tanshinol, (Rac)-Danshensu |
| Molecular Weight | 198.17 |
| Formula | C9H10O5 |
| Cas No. | 23028-17-3 |
| Smiles | O=C(O)C(O)CC1=CC=C(O)C(O)=C1 |
| Color | Yellow |
| Appearance | Solid |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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