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Anti-TLR3 Antibody (4T47)
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Catalog No. TMAY-03149
Alias toll like receptor 3, IIAE2, CD283
Anti-TLR3 Antibody (4T47) is a Rabbit antibody targeting TLR3. Anti-TLR3 Antibody (4T47) can be used in ELISA.
Anti-TLR3 Antibody (4T47)
Anti-TLR3 Antibody (4T47)
😃Good
Catalog No. TMAY-03149Alias toll like receptor 3, IIAE2, CD283
Anti-TLR3 Antibody (4T47) is a Rabbit antibody targeting TLR3. Anti-TLR3 Antibody (4T47) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Mouse |
| Alias | toll like receptor 3, IIAE2, CD283 |
| Ig Type | Rabbit IgG |
| Clone | 4T47 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TLR3 / CD283 (TMPY-01396; NP_569054.2; Met1-Leu705). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Toll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a member of the Toll-like receptor family of pattern recognition receptors of the innate immune system. TLR3/CD283 plays a fundamental role in pathogen recognition and activation of innate immunity. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA, a sign of viral infection. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse TLR3 / CD283 protein (TMPY-01396) |
| Antigen Species | Mouse |
| Biology Area | Neuroinflammation, Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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