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Anti-TLR3 Antibody (4T47)

😃Good
Catalog No. TMAY-03149
Alias toll like receptor 3, IIAE2, CD283

Anti-TLR3 Antibody (4T47) is a Rabbit antibody targeting TLR3. Anti-TLR3 Antibody (4T47) can be used in ELISA.

Anti-TLR3 Antibody (4T47)

Anti-TLR3 Antibody (4T47)

😃Good
Catalog No. TMAY-03149Alias toll like receptor 3, IIAE2, CD283
Anti-TLR3 Antibody (4T47) is a Rabbit antibody targeting TLR3. Anti-TLR3 Antibody (4T47) can be used in ELISA.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Anti-TLR3 Antibody (4T47) is a Rabbit antibody targeting TLR3. Anti-TLR3 Antibody (4T47) can be used in ELISA.
Aliastoll like receptor 3, IIAE2, CD283
Ig Type
Monoclonal Rabbit IgG
Clone
4T47
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse TLR3 / CD283 (TMPY-01396; NP_569054.2; Met1-Leu705).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundToll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a member of the Toll-like receptor family of pattern recognition receptors of the innate immune system. TLR3/CD283 plays a fundamental role in pathogen recognition and activation of innate immunity. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA, a sign of viral infection. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse TLR3 / CD283 protein (TMPY-01396)
Antigen Species
Mouse
Biology Area
Neuroinflammation, Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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