keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation. In a mouse model of implanted fibrosarcoma, Chlorin E6 (2.5-10 mg/kg, i.v., 50-200 J/cm2 irradiation) resulted in complete tumor disappearance after varying degrees of irradiation. Agents including Chlorin E6 were tested in a Phase I clinical study in patients with early superficial squamous cell carcinoma of bronchial origin with favorable results (40 mg/m2, IV, 100 J/cm2 laser irradiation). In a Phase II clinical trial in patients with early stage lung cancer, the same mode of administration resulted in a complete response in 82.9% of patients. Chlorin E6 has been investigated as a nanotechnology drug delivery tool.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 30.00 | |
25 mg | In stock | $ 44.00 | |
50 mg | In stock | $ 64.00 | |
100 mg | In stock | $ 105.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 35.00 |
Description | Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation. In a mouse model of implanted fibrosarcoma, Chlorin E6 (2.5-10 mg/kg, i.v., 50-200 J/cm2 irradiation) resulted in complete tumor disappearance after varying degrees of irradiation. Agents including Chlorin E6 were tested in a Phase I clinical study in patients with early superficial squamous cell carcinoma of bronchial origin with favorable results (40 mg/m2, IV, 100 J/cm2 laser irradiation). In a Phase II clinical trial in patients with early stage lung cancer, the same mode of administration resulted in a complete response in 82.9% of patients. Chlorin E6 has been investigated as a nanotechnology drug delivery tool. |
Synonyms | Ce6, Chlorin e6, CE6 |
Molecular Weight | 596.67 |
Formula | C34H36N4O6 |
CAS No. | 19660-77-6 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11.93 mg/mL (20 mM)
DMF: 11.93 mg/mL (20 mM)
Ethanol: Slightly Soluble
You can also refer to dose conversion for different animals. More
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Chlorin E6 19660-77-6 Microbiology/Virology Parasite CE 6 Ce6 CE-6 Chlorin e6 CE6 inhibitor inhibit