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Anti-MST3 Antibody (8S853)

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Catalog No. TMAC-02664
Alias STK3, STE20, serine/threonine kinase 24, RP11-111L24.5, MST3B, MST3, HEL-S-95

Anti-MST3 Antibody (8S853) is a Mouse antibody targeting MST3. Anti-MST3 Antibody (8S853) can be used in WB,IP,IF.

Anti-MST3 Antibody (8S853)

Anti-MST3 Antibody (8S853)

😃Good
Catalog No. TMAC-02664Alias STK3, STE20, serine/threonine kinase 24, RP11-111L24.5, MST3B, MST3, HEL-S-95
Anti-MST3 Antibody (8S853) is a Mouse antibody targeting MST3. Anti-MST3 Antibody (8S853) can be used in WB,IP,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4277-10 days
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Product Introduction

Bioactivity
Description
Anti-MST3 Antibody (8S853) is a Mouse antibody targeting MST3. Anti-MST3 Antibody (8S853) can be used in WB,IP,IF.
SynonymsSTK3, STE20, serine/threonine kinase 24, RP11-111L24.5, MST3B, MST3, HEL-S-95
Clone
8S853
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of MST-3 expression in non-transfected 293T (A), human MST-3 transfected 293T (B) and A-431 (C) whole cell lysates.
2. Immunofluorescence staining of HeLa cells showing cytoplasmic staining.
Application
Recommended Dose
WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundSterile-20 (STE20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to STE20 are divided into two groups, the PAK subfamily and the GCK subfamily. The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42-binding site, and these kinases can activate both p38 MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an N-terminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK, JNK, p38 MAPK, and caspase-3. The mammalian STE20-like kinases (MST kinases, also known as Ksr proteins) are members of the GCK subfamily. Ksr-1 and Ksr-2 (also known as MST-2 and MST-1, respectively) are both direct substrates of caspase-3 that accelerate caspase-3 activation. MST-3 is ubiquitously expressed in mammalian tissue and can phosphorylate exogenous substrates as well as itself. MST-4 is highly expressed in placenta, thymus, and peripheral blood leukocytes, and it specifically activates ERK.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Amino acids 275-393 of MST-3 of human origin
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 50/35 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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