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Anti-IL-T3 Antibody (4M315)
😃Good
Catalog No. TMAY-02830
Alias LIR-5, LIR5, leukocyte immunoglobulin like receptor B4, ILT-3, ILT3, CD85K
Anti-IL-T3 Antibody (4M315) is a Mouse antibody targeting IL-T3. Anti-IL-T3 Antibody (4M315) can be used in FCM.
Anti-IL-T3 Antibody (4M315)
Anti-IL-T3 Antibody (4M315)
😃Good
Catalog No. TMAY-02830Alias LIR-5, LIR5, leukocyte immunoglobulin like receptor B4, ILT-3, ILT3, CD85K
Anti-IL-T3 Antibody (4M315) is a Mouse antibody targeting IL-T3. Anti-IL-T3 Antibody (4M315) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: FCM Reactivity: Human |
| Alias | LIR-5, LIR5, leukocyte immunoglobulin like receptor B4, ILT-3, ILT3, CD85K |
| Ig Type | Mouse IgG1 |
| Clone | 4M315 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human LILRB4(CD85k) expression on human whole blood monocytes. Cells were stained with purified anti-Human LILRB4(CD85k), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LILRB4/CD85k/ILT3 (rh LILRB4/CD85k/ILT3; TMPY-04650; NP_001265357.2; Met1-Glu259). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | LILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a Protein Coding gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1. LILRB4 is associated with the pathological processes of various inflammatory diseases. The LILRB4 is a central inhibitory receptor in Uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Human LILRB4/CD85k/ILT3 Protein (TMPY-04650) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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