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Anti-IL-T3 Antibody (4M315) (Synonyms: LIR-5, LIR5, leukocyte immunoglobulin like receptor B4, ILT-3, ILT3||...)

Catalog No. TMAY-02830 Copy Product Info
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Anti-IL-T3 Antibody (4M315) is a Mouse antibody targeting IL-T3. Anti-IL-T3 Antibody (4M315) can be used in FCM.

Anti-IL-T3 Antibody (4M315)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02830
Synonyms LIR-5, LIR5, leukocyte immunoglobulin like receptor B4, ILT-3, ILT3, CD85K

Anti-IL-T3 Antibody (4M315) is a Mouse antibody targeting IL-T3. Anti-IL-T3 Antibody (4M315) can be used in FCM.

Anti-IL-T3 Antibody
(4M315)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-T3 Antibody (4M315) is a Mouse antibody targeting IL-T3. Anti-IL-T3 Antibody (4M315) can be used in FCM.
SynonymsLIR-5, LIR5, leukocyte immunoglobulin like receptor B4, ILT-3, ILT3, CD85K
Ig Type
Mouse IgG1
Clone
4M315
Reactivity
Human
Specificity
Human ILT3/LILRB4
Verified Activity
Flow cytometric analysis of Human LILRB4(CD85k) expression on human whole blood monocytes. Cells were stained with purified anti-Human LILRB4(CD85k), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
Application
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LILRB4/CD85k/ILT3 (rh LILRB4/CD85k/ILT3; TMPY-04650; NP_001265357.2; Met1-Glu259). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a Protein Coding gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1. LILRB4 is associated with the pathological processes of various inflammatory diseases. The LILRB4 is a central inhibitory receptor in Uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Human LILRB4/CD85k/ILT3 Protein (TMPY-04650)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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