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E-3620

Name: E-3620
Brand: TargetMol
SKU: T62107
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T62107Cas No. 151213-86-4

E-3620 is a novel 5-HT3 receptor antagonist that inhibits cisplatin-induced vomiting in beagles. E-3620 can be used to study dyskinesia, gastrointestinal dyskinesia, psoriasis and psoriasis.

E-3620

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Purity: 98.88%

Catalog No. T62107Cas No. 151213-86-4

E-3620 is a novel 5-HT3 receptor antagonist that inhibits cisplatin-induced vomiting in beagles. E-3620 can be used to study dyskinesia, gastrointestinal dyskinesia, psoriasis and psoriasis.

Pack Size	Price	Availability	Quantity
1 mg	$149	In Stock
1 mL x 10 mM (in DMSO)	$29	6-8 weeks

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Purity:98.88%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

E-3620 is a novel 5-HT3 receptor antagonist that inhibits cisplatin-induced vomiting in beagles. E-3620 can be used to study dyskinesia, gastrointestinal dyskinesia, psoriasis and psoriasis.

Chemical Properties

Molecular Weight	412.35
Formula	C₂₀H₂₇Cl₂N₃O₂
Cas No.	151213-86-4
Smiles	Cl.CC#C[C@H](C)Oc1cc(N)c(Cl)cc1C(=O)N[C@@H]1C[C@@H]2CC[C@H](C1)N2C

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (194.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4251 mL	12.1256 mL	24.2512 mL	121.2562 mL
5 mM	0.4850 mL	2.4251 mL	4.8502 mL	24.2512 mL
10 mM	0.2425 mL	1.2126 mL	2.4251 mL	12.1256 mL
20 mM	0.1213 mL	0.6063 mL	1.2126 mL	6.0628 mL
50 mM	0.0485 mL	0.2425 mL	0.4850 mL	2.4251 mL
100 mM	0.0243 mL	0.1213 mL	0.2425 mL	1.2126 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc