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Anti-RhoA Antibody (6T350) (Synonyms: RHOH12, RHO12, ras homolog family member A, ARHA, ARH12)

Catalog No. TMAY-02349 Copy Product Info
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Anti-RhoA Antibody (6T350) is a Mouse antibody targeting RhoA. Anti-RhoA Antibody (6T350) can be used in ELISA.

Anti-RhoA Antibody (6T350)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02349
Synonyms RHOH12, RHO12, ras homolog family member A, ARHA, ARH12

Anti-RhoA Antibody (6T350) is a Mouse antibody targeting RhoA. Anti-RhoA Antibody (6T350) can be used in ELISA.

Anti-RhoA Antibody
(6T350)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-RhoA Antibody (6T350) is a Mouse antibody targeting RhoA. Anti-RhoA Antibody (6T350) can be used in ELISA.
SynonymsRHOH12, RHO12, ras homolog family member A, ARHA, ARH12
Ig Type
Mouse IgG1
Clone
6T350
Reactivity
Human
Specificity
Human RhoA
No cross-reactivity in ELISA with
Insect cell lysate
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RhoA (rh RhoA; TMPY-01958; P61586-1; Met 1-Leu 193). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTransforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that belongs to the small GTPase superfamily and Rho family. The Rho family of small GTPases plays a key role in the dynamic regulation of the actin cytoskeleton that underlies various important cellular functions such as shape changes, migration, and polarity. RHOA / ARH12 is part of a larger family of related proteins known as the Ras superfamily; proteins involved in the regulation and timing of cell division. RHOA / ARH12 is a small GTPase protein known to regulate the actin cytoskeleton in the formation of stress fibers. It acts upon two known effector proteins: ROCK1 (Rho-associated, coiled-coil containing protein kinase 1) and DIAPH1 ( diaphanous homolog 1 (Drosophila) ). RHOA / ARH12 regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. RHOA / ARH12 serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. RHOA / ARH12 may be an activator of PLCE1. It is activated by ARHGEF2, which promotes the exchange of GDP for GTP.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human RhoA protein (TMPY-01958)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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