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Anti-GATA3 Antibody (4T104)
Catalog No. TMAB-06353 Copy Product Info
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Anti-GATA3 Antibody (4T104) is a Mouse antibody targeting GATA3. Anti-GATA3 Antibody (4T104) can be used in WB,ICC/IF,FCM.
Anti-GATA3 Antibody (4T104)
Copy Product Info🥰Excellent
Catalog No. TMAB-06353
Anti-GATA3 Antibody (4T104) is a Mouse antibody targeting GATA3. Anti-GATA3 Antibody (4T104) can be used in WB,ICC/IF,FCM.
Anti-GATA3 Antibody
(4T104)
(4T104)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-GATA3 Antibody (4T104) is a Mouse antibody targeting GATA3. Anti-GATA3 Antibody (4T104) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG2b,k |
| Clone | 4T104 |
| Reactivity | Human |
| Verified Activity | Sample: Lane 1: CEM cell lysates Lane 2: HL60 cell lysates Lane 3: SH-SY5Y cell lysates Primary: Anti-GATA3 (TMAB-06353) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 52 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | T-cells and endothelial cells. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites. |
| Immunogen | Recombinant Protein: human GATA3 |
| Antigen Species | Human |
| Gene Name | GATA3 |
| Gene ID | |
| Protein Name | Trans-acting T-cell-specific transcription factor GATA-3 |
| Uniprot ID | |
| Function | Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. |
| Molecular Weight | Theoretical: 49 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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