Powder: -20°C for 3 years
In solvent: -80°C for 2 years
AhR antagonist 5 free base is an orally active antagonist of AhR with IC50s of ~35-150 nM in human and rodent cell lines.
Description | AHR antagonist 5 free base is an orally active antagonist of AHR with IC50s of ~35-150 nM in human and rodent cell lines. |
In vitro | AHR antagonist 5 free base induces an activated human T cell state and inhibits CYP1A1 and interleukin (IL)-22 gene expression. AHR antagonist 5 increases pro-inflammatory cytokines, such as IL-2 and IL-9[1]. |
Molecular Weight | 441.5 |
Formula | C25H24FN7 |
CAS No. | 2247950-42-9 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 50 mg/mL (113.25 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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AHR antagonist 5 free base 2247950-42-9 Immunology/Inflammation Aryl Hydrocarbon Receptor Inhibitor inhibitor inhibit