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Anti-OX40/TNFRSF4 Antibody (5W381)
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Catalog No. TMAY-00886
Alias TXGP1L, tumor necrosis factor receptor superfamily, member 4, OX40, IMD16, CD134, ACT35
Anti-OX40/TNFRSF4 Antibody (5W381) is a Mouse antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody (5W381) can be used in ELISA.
Anti-OX40/TNFRSF4 Antibody (5W381)
Anti-OX40/TNFRSF4 Antibody (5W381)
😃Good
Catalog No. TMAY-00886Alias TXGP1L, tumor necrosis factor receptor superfamily, member 4, OX40, IMD16, CD134, ACT35
Anti-OX40/TNFRSF4 Antibody (5W381) is a Mouse antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody (5W381) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $93 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | TXGP1L, tumor necrosis factor receptor superfamily, member 4, OX40, IMD16, CD134, ACT35 |
| Ig Type | Mouse IgG1 |
| Clone | 5W381 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human OX40/TNFRSF4/CD134 (rh OX40/TNFRSF4/CD134; TMPY-01423; NP_003318.1; Met1-Ala216). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between OX40 and OX40L plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX40-OX40L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX40 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human OX40/TNFRSF4/CD134 Protein (TMPY-01423) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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