Shopping Cart

Your shopping cart is currently empty

LNA-Adenosine

Name: LNA-Adenosine
Brand: TargetMol
SKU: T32826
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

🥰Excellent

Catalog No. T32826Cas No. 206055-70-1

Alias LNA-A, LNA Adenosine, 2'-O,4'-C-Methyleneadenosine

LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.

LNA-Adenosine

Copy Product Info

🥰Excellent

Purity: 99.15%

Catalog No. T32826Alias LNA-A, LNA Adenosine, 2'-O,4'-C-MethyleneadenosineCas No. 206055-70-1

LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 mg	$29	In Stock	In Stock
50 mg	Inquiry	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.15%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

LNA-Adenosine AI Summary

LNA-Adenosine exhibits both agonist and antagonist activities at the human adenosine A3 receptor, with EC50 and IC50 values greater than 100,000.0 nM observed after 15 to 30 minutes. Additionally, the compound shows antiviral activity against wild type Hepatitis C virus genotype 1b in human HuH7 cells, with an EC50 value greater than 50,000.0 nM, indicating limited potency in inhibiting the virus at this concentration..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.
Synonyms	LNA-A, LNA Adenosine, 2'-O,4'-C-Methyleneadenosine

Chemical Properties

Molecular Weight	279.25
Formula	C₁₁H₁₃N₅O₄
Cas No.	206055-70-1
Smiles	C(O)[C@@]12O[C@H]([C@@]([C@@H]1O)(OC2)[H])N3C=4C(N=C3)=C(N)N=CN4
Relative Density.	2.14 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (196.96 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5810 mL	17.9051 mL	35.8102 mL	179.0510 mL
5 mM	0.7162 mL	3.5810 mL	7.1620 mL	35.8102 mL
10 mM	0.3581 mL	1.7905 mL	3.5810 mL	17.9051 mL
20 mM	0.1791 mL	0.8953 mL	1.7905 mL	8.9526 mL
50 mM	0.0716 mL	0.3581 mL	0.7162 mL	3.5810 mL
100 mM	0.0358 mL	0.1791 mL	0.3581 mL	1.7905 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc