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Anti-EIF5A2 Antibody (3T444)

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Catalog No. TMAY-02775
Alias eukaryotic translation initiation factor 5A2, eIF5AII, EIF-5A2

Anti-EIF5A2 Antibody (3T444) is a Rabbit antibody targeting EIF5A2. Anti-EIF5A2 Antibody (3T444) can be used in ELISA.

Anti-EIF5A2 Antibody (3T444)

Anti-EIF5A2 Antibody (3T444)

😃Good
Catalog No. TMAY-02775Alias eukaryotic translation initiation factor 5A2, eIF5AII, EIF-5A2
Anti-EIF5A2 Antibody (3T444) is a Rabbit antibody targeting EIF5A2. Anti-EIF5A2 Antibody (3T444) can be used in ELISA.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Anti-EIF5A2 Antibody (3T444) is a Rabbit antibody targeting EIF5A2. Anti-EIF5A2 Antibody (3T444) can be used in ELISA.
Aliaseukaryotic translation initiation factor 5A2, eIF5AII, EIF-5A2
Ig Type
Monoclonal Rabbit IgG
Clone
3T444
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human EIF5A2 (rh EIF5A2; TMPY-03795; Q9GZV4; Met1-Lys153).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundEukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted in the downregulation of the tumorigenic proteins, apoptosis regulator Bcl-2 and myc proto-oncogene protein, and upregulation of E-cadherin, suggesting that EIF5A2 promotes proliferation and metastasis through these proteins. EIF5A2 may therefore serve as a novel therapeutic target for the treatment of NSCLC. EIF5A2 might be a novel therapeutic target for the inhibition of NPC progress. EIF5A2 overexpression may contribute to cancer progression and poor prognosis, it could be a novel potential prognostic marker for FIGO stage I-II cervical cancer. EIF5A2 upregulation plays an important oncogenic role in gastric cancer. EIF5A2 may represent a new predictor for poor survival and is a potential therapeutic target for gastric cancer. The eukaryotic initiation factor 5A2 (EIF5A2) over-expression enhances HCC cell metastasis. EIF5A2, as a target of PI3K/Akt, promotes melanoma cell invasion and may serve as a promising prognostic marker and a potential therapeutic target for melanoma.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human EIF5A2 Protein (TMPY-03795)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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