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L-Glutamic acid monosodium salt monohydrate

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Catalog No. T35369Cas No. 6106-04-3
Alias MSG monohydrate, Monosodium L-glutamate monohydrate, L(+)-Monosodium glutamate monohydrate

L-Glutamic acid monosodium salt monohydrate (MSG monohydrate) is an important food additive with gastrointestinal protective effects. It plays a critical role in nutrient metabolism, energy demand, immune response, oxidative stress, signal transduction, and synaptic transmission. L-Glutamic acid monosodium salt monohydrate can induce oxidative stress, DNA damage, and apoptosis in mouse liver and brain tissues. It can protect against gastrointestinal damage caused by NSAIDs and Helicobacter pylori through multiple mechanisms.

L-Glutamic acid monosodium salt monohydrate
Other Forms of L-Glutamic acid monosodium salt monohydrate:

L-Glutamic acid monosodium salt monohydrate

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Purity: 99.98%
Catalog No. T35369Alias MSG monohydrate, Monosodium L-glutamate monohydrate, L(+)-Monosodium glutamate monohydrateCas No. 6106-04-3
L-Glutamic acid monosodium salt monohydrate (MSG monohydrate) is an important food additive with gastrointestinal protective effects. It plays a critical role in nutrient metabolism, energy demand, immune response, oxidative stress, signal transduction, and synaptic transmission. L-Glutamic acid monosodium salt monohydrate can induce oxidative stress, DNA damage, and apoptosis in mouse liver and brain tissues. It can protect against gastrointestinal damage caused by NSAIDs and Helicobacter pylori through multiple mechanisms.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 mg$30In StockIn Stock
1 g$40In StockIn Stock
5 g$106-In Stock
10 g$156-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.98%
Appearance:Solid
Color:White
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
L-Glutamic acid monosodium salt monohydrate (MSG monohydrate) is an important food additive with gastrointestinal protective effects. It plays a critical role in nutrient metabolism, energy demand, immune response, oxidative stress, signal transduction, and synaptic transmission. L-Glutamic acid monosodium salt monohydrate can induce oxidative stress, DNA damage, and apoptosis in mouse liver and brain tissues. It can protect against gastrointestinal damage caused by NSAIDs and Helicobacter pylori through multiple mechanisms.
In vitro
L-Glutamic acid monosodium salt monohydrate can lead to oxidative stress-mediated DNA damage and apoptosis. [1]
In vivo
L-Glutamic acid monosodium salt monohydrate can be used to induce obesity in animal models. [1]
SynonymsMSG monohydrate, Monosodium L-glutamate monohydrate, L(+)-Monosodium glutamate monohydrate
Chemical Properties
Molecular Weight187.13
FormulaC5H10NNaO5
Cas No.6106-04-3
SmilesOC(CC[C@H](N)C([O-])=O)=O.[Na+].O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 80 mg/mL (427.51 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM5.3439 mL26.7194 mL53.4388 mL267.1939 mL
5 mM1.0688 mL5.3439 mL10.6878 mL53.4388 mL
10 mM0.5344 mL2.6719 mL5.3439 mL26.7194 mL
20 mM0.2672 mL1.3360 mL2.6719 mL13.3597 mL
50 mM0.1069 mL0.5344 mL1.0688 mL5.3439 mL
100 mM0.0534 mL0.2672 mL0.5344 mL2.6719 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MSGMonosodium L-glutamateLMonosodium glutamate MonohydrateLMonosodium glutamateL-Glutamic acid monosodium salt monohydrateL-Glutamic acid monosodium MonohydrateL-Glutamic acidL(+)Monosodium glutamate monohydrateL(+) Monosodium glutamate monohydrate
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