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ADR-851 free base

Name: ADR-851 free base
Brand: TargetMol
SKU: T23642
Price: 293 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T23642Cas No. 138559-56-5

Alias ADR851 free base, ADR 851 free base

ADR-851 free base (ADR 851 free base) is a 5-HT3 receptor antagonist and a novel antiemetic with analgesic activity.

ADR-851 free base

🥰Excellent

Purity: 98.39%

Catalog No. T23642Alias ADR851 free base, ADR 851 free baseCas No. 138559-56-5

ADR-851 free base (ADR 851 free base) is a 5-HT3 receptor antagonist and a novel antiemetic with analgesic activity.

Pack Size	Price	Availability
1 mg	$293	In Stock
5 mg	$722	In Stock
10 mg	$987	In Stock
25 mg	$1,520	In Stock
50 mg	$1,980	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:98.39%

ee:100%

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Product Introduction

Bioactivity

Description	ADR-851 free base (ADR 851 free base) is a 5-HT3 receptor antagonist and a novel antiemetic with analgesic activity.
In vivo	Male Sprague-Dawley rats were injected intraperitoneally with ADR-851 (0.1-10 mg/kg), and the ADR-851 isoforms were not analgesic in either the thermal or mechanical tests; ADR-851R produced significant analgesia in the formalin test at doses of 3 mg/kg and 10 mg/kg.[1]
Synonyms	ADR851 free base, ADR 851 free base

Chemical Properties

Molecular Weight	295.77
Formula	C₁₄H₁₈ClN₃O₂
Cas No.	138559-56-5
Smiles	C(NC[C@@H]1CCCN1)(=O)C2=C3C(=C(N)C(Cl)=C2)CCO3
Relative Density.	1.314 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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