Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 38.00 | |
5 mg | In stock | $ 89.00 | |
10 mg | In stock | $ 147.00 | |
25 mg | In stock | $ 313.00 | |
50 mg | In stock | $ 528.00 | |
100 mg | In stock | $ 769.00 | |
500 mg | In stock | $ 1,580.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 109.00 |
Description | SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4. |
Targets&IC50 | TRPV2:0.46 μM |
In vitro | In PC-3M cells, SET 2 (20 μM) suppresses cell migration without inhibiting cell viability and inhibits 2-APB-evoked current transiently co-transfected with TRPV2 and LPAR1[1]. |
Molecular Weight | 402.43 |
Formula | C17H21F3N4O2S |
CAS No. | 2313525-20-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 36.2 mg/mL (90.0 mM)
Ethanol: 20.12 mg/mL(50 mM)
You can also refer to dose conversion for different animals. More
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SET 2 2313525-20-9 Membrane transporter/Ion channel TRP/TRPV Channel SET2 SET-2 inhibitor inhibit