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BI-6901

Name: BI-6901
Brand: TargetMol
SKU: T36478
Price: 199 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36478Cas No. 2040401-92-9

BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.

BI-6901

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Purity: 99.94%

Catalog No. T36478Cas No. 2040401-92-9

BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$199	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.94%

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COA

Product Introduction

Bioactivity

Description	BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.
In vivo	When administered at 100 mg/kg ip bid, BI-6901 is effective in a mouse contact hypersensitivity (CHS) model induced by DNFB, and it dose-dependently inhibits the inflammatory response in DNFB-sensitized Balb-C mice[1].

Chemical Properties

Molecular Weight	453.56
Formula	C₂₃H₂₇N₅O₃S
Cas No.	2040401-92-9
Smiles	CC1CCN(CC1)C(=O)[C@@H](CCn1cccc1C#N)NS(=O)(=O)c1cccc2[nH]ccc12
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 120 mg/mL (264.57 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 5 mg/mL (11.02 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2048 mL	11.0239 mL	22.0478 mL	110.2390 mL
5 mM	0.4410 mL	2.2048 mL	4.4096 mL	22.0478 mL
10 mM	0.2205 mL	1.1024 mL	2.2048 mL	11.0239 mL
20 mM	0.1102 mL	0.5512 mL	1.1024 mL	5.5119 mL
50 mM	0.0441 mL	0.2205 mL	0.4410 mL	2.2048 mL
100 mM	0.0220 mL	0.1102 mL	0.2205 mL	1.1024 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc