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Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39)
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Catalog No. TMAB-07699
Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) is a Mouse antibody targeting Influenza A virus Nucleoprotein H1N1. Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) can be used in WB.
Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39)
Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39)
😃Good
Catalog No. TMAB-07699
Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) is a Mouse antibody targeting Influenza A virus Nucleoprotein H1N1. Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) is a Mouse antibody targeting Influenza A virus Nucleoprotein H1N1. Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) can be used in WB. |
| Ig Type | IgG |
| Clone | 9T39 |
| Reactivity | Influenza A Nucleoprotein [A/Victoria/4897/2022 (H1N1)] |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion). |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002). |
| Immunogen | Recombinant Protein: Influenza A virus H1N1(A/Victoria/4897/2022)Nucleoprotein |
| Antigen Species | Influenza A virus |
| Gene Name | NP |
| Gene ID | |
| Protein Name | Nucleoprotein |
| Function | Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation. |
| Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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