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M6903
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Catalog No. T9901A-851 Copy Product Info
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M6903 is a humanized IgG2 monoclonal antibody that targets T-cell immunoglobulin and mucin domain 3 (TIM-3), with a binding affinity (KD) of 2.3 nM for human TIM-3. By binding to TIM-3, M6903 blocks the interaction of TIM-3 with phosphatidylserine (PtdSer), carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), and galectin-9 (Gal-9). This blockade helps alleviate TIM-3-mediated T-cell inhibition, promoting antigen-specific T-cell activation and enhancing antitumor immunity. M6903 holds promise for cancer research.
M6903
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Storage & Solubility Information
| Description | M6903 is a humanized IgG2 monoclonal antibody that targets T-cell immunoglobulin and mucin domain 3 (TIM-3), with a binding affinity (KD) of 2.3 nM for human TIM-3. By binding to TIM-3, M6903 blocks the interaction of TIM-3 with phosphatidylserine (PtdSer), carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), and galectin-9 (Gal-9). This blockade helps alleviate TIM-3-mediated T-cell inhibition, promoting antigen-specific T-cell activation and enhancing antitumor immunity. M6903 holds promise for cancer research. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | TIM-3 |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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