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Anti-CD3 Antibody (OKT-3, humanized)
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Catalog No. T9901A-150 Copy Product Info
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Anti-CD3 Antibody (OKT-3, humanized) is a humanized OKT3-derived anti-CD3 antibody developed based on Muromonab-CD3 (OKT3, T76719), with reduced immunogenicity relative to the original murine antibody. Anti-CD3 Antibody (OKT-3, humanized) is applicable to immunological research involving T-cell receptor signaling, lymphocyte activation, and immune modulation in translational and preclinical experimental systems.
Anti-CD3 Antibody
(OKT-3, humanized)
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $163 | - | In Stock | |
| 5 mg | $496 | - | In Stock | |
| 10 mg | $795 | - | In Stock | |
| 25 mg | $1,470 | - | In Stock | |
| 50 mg | $2,350 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.5% (SDS-PAGE); 98.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Anti-CD3 Antibody (OKT-3, humanized) is a humanized OKT3-derived anti-CD3 antibody developed based on Muromonab-CD3 (OKT3, T76719), with reduced immunogenicity relative to the original murine antibody. Anti-CD3 Antibody (OKT-3, humanized) is applicable to immunological research involving T-cell receptor signaling, lymphocyte activation, and immune modulation in translational and preclinical experimental systems. |
| In vitro | Method: HuCD3εHET cells were incubated for 24-36 h with Anti-CD3 Antibody (OKT-3, humanized) (1.0 μg/mL) Result: Anti-CD3 Antibody (OKT-3) decreases CD4+ and CD8+ T cell numbers in huCD3εHET cells[1]. |
| In vivo | Method: 6–10 weeks-old huCD3Εhet mice (500 μg/Mouse) were injected i.p. with Anti-CD3 Antibody (OKT-3, humanized). Result: Anti-CD3 Antibody (OKT-3, humanized) injection led to decreased T cell numbers in huCD3εHET mice[1]. |
| Application | Functional assay |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Molecular Weight | 145.65 kDa (Predicted) |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature, -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Anti-CD3 Antibody (OKT-3, humanized) in vivo | Anti-CD3 Antibody (OKT-3, humanized) in vitro | Anti-CD3 Antibody (OKT-3, humanized) molecular weight
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