t-3

Liothyronine (Tresitope) is a synthetic and highly active thyroid hormone that acts as an effective agonist of TRα and TRβ (Ki = 2.33 nM for both hTRα and hTRβ). It activates the TRβ1 receptor, promotes the metabolism of carbohydrates, proteins, and fats, accelerates the oxidative processes in tissue cells, maintains basal metabolic rate, and supports normal growth and development. Liothyronine can be used to induce hyperthyroidism models.

Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).

Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells.

Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.

T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite

CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.

T3-ATA S-isomer, the S-isomer of T3-ATA, represents the active form of the thyroid hormone.

Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine.

Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities. It can be used to study hypothyroidism, stroke and cognitive dysfunction.

T3Inh-1 is a potent and selective ppGalNAc-T3 inhibitor with IC50 of 7 µM. T3Inh-1 protects against breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in tissue cells and mice without causing any toxic side effects.

Anti-Human CD3 Antibody (UCHT1 (Leu-4) (T3)) is a monoclonal antibody targeting human CD3 and can be used in immunological research.

3,3',5-Triiodothyronine-(tyrosine ring-13C6) is the 13C labeled compound of 3,3',5-Triiodothyronine. 3,3',5-Triiodothyronine has a CAS number of 5817-39-0.

REVERSE T3 (Standard) is a reference standard for research and analysis in studies involving REVERSE T3. Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.

Reverse Triiodothyronine-[Diiodophenyl-Ring-13C6] (Rev T3)(01.N Ammonia) (Standard) is a reference standard of Reverse Triiodothyronine-[Diiodophenyl-Ring-13C6] (Rev T3)(01.N Ammonia) intended for quantitative analysis, quality control, and related biochemical research applications.

T3 Peptide is an active fragment of tumstatin. By binding to integrins αvβ3/αvβ5, it activates the PI3K/Akt/p70S6K signaling pathway, thereby promoting the proliferation and migration of rat cardiac fibroblasts.

Dextran T3 (MW 3,000) is a dehydrated glucose polymer with an average molecular weight of 3,000. It exhibits excellent biodegradability and biocompatibility, making it suitable for use in food, pharmaceuticals, cosmetics, and research applications.

T3-KLH is a hapten-carrier protein conjugate formed by coupling T3 (thyroxine) to keyhole limpet hemocyanin (KLH). As a hapten, T3 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. T3-KLH may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M PBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

T3-OVA is a hapten-carrier protein conjugate formed by coupling T3 (thyroxine) to chicken ovalbumin (OVA). As a hapten, T3 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.

T3-BSA is a hapten-carrier protein conjugate formed by coupling T3 (thyroxine) to bovine serum albumin (BSA). As a hapten, T3 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.

KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by affecting intracellular calcium mobilization in atrial muscle cells.KT-362 fumarate has a relaxing effect on femoral and basilar artery strips in rabbits.

VRT-325 can repair folding defects by promoting dimerization of the two NBDs or by promoting folding of the TMD.VRT-325 accelerates the healing rate of CF cell monolayers.

MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).

methyl4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-yn-2-yl)oxy)benzoate is a useful compound for the synthesis of a variety of organic compounds.

methyl(Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate is a useful compound for the synthesis of a variety of organic compounds.