t3

Liothyronine (Tresitope) is a synthetic and highly active thyroid hormone that acts as an effective agonist of TRα and TRβ (Ki = 2.33 nM for both hTRα and hTRβ). It activates the TRβ1 receptor, promotes the metabolism of carbohydrates, proteins, and fats, accelerates the oxidative processes in tissue cells, maintains basal metabolic rate, and supports normal growth and development. Liothyronine can be used to induce hyperthyroidism models.

T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite

T3 Peptide is an active fragment of tumstatin. By binding to integrins αvβ3/αvβ5, it activates the PI3K/Akt/p70S6K signaling pathway, thereby promoting the proliferation and migration of rat cardiac fibroblasts.

Dextran T3 (MW 3,000) is a dehydrated glucose polymer with an average molecular weight of 3,000. It exhibits excellent biodegradability and biocompatibility, making it suitable for use in food, pharmaceuticals, cosmetics, and research applications.

T3-KLH is a hapten-carrier protein conjugate formed by coupling T3 (thyroxine) to keyhole limpet hemocyanin (KLH). As a hapten, T3 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. T3-KLH may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M PBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

T3-OVA is a hapten-carrier protein conjugate formed by coupling T3 (thyroxine) to chicken ovalbumin (OVA). As a hapten, T3 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.

T3-BSA is a hapten-carrier protein conjugate formed by coupling T3 (thyroxine) to bovine serum albumin (BSA). As a hapten, T3 alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.

3,3',5-Triiodothyronine-(tyrosine ring-13C6) is the 13C labeled compound of 3,3',5-Triiodothyronine. 3,3',5-Triiodothyronine has a CAS number of 5817-39-0.

Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.

CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.

T3-ATA S-isomer, the S-isomer of T3-ATA, represents the active form of the thyroid hormone.

T3Inh-1 is a potent and selective ppGalNAc-T3 inhibitor with IC50 of 7 µM. T3Inh-1 protects against breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in tissue cells and mice without causing any toxic side effects.

REVERSE T3 (Standard) is a reference standard for research and analysis in studies involving REVERSE T3. Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.

Reverse Triiodothyronine-[Diiodophenyl-Ring-13C6] (Rev T3)(01.N Ammonia) (Standard) is a reference standard of Reverse Triiodothyronine-[Diiodophenyl-Ring-13C6] (Rev T3)(01.N Ammonia) intended for quantitative analysis, quality control, and related biochemical research applications.

Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).

Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells.

Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine.

Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities. It can be used to study hypothyroidism, stroke and cognitive dysfunction.

Liothyronine (Standard) is a standard reference substance for analytical research and assay. Liothyronine (Tresitope) is a synthetic highly active thyroid hormone and a potent agonist of TRα and TRβ (with Ki values of 2.33 nM for both hTRα and hTRβ). It activates TRβ1 receptors, promotes the metabolism of carbohydrates, proteins and lipids, accelerates oxidative processes in tissue cells, maintains basal metabolic rate, and contributes to body growth and development. It can be used to induce hyperthyroidism animal models.

Triiodothyronine-13C6 hydrochloride is the 13C labeled compound of 3,3',5-Triiodothyronine hydrochloride.

Triiodothyronine-13C6 Hydrochloride (Standard) is a reference standard of Triiodothyronine-13C6 Hydrochloride intended for quantitative analysis, quality control, and related biochemical research applications. 3,3',5-Triiodothyronine-(tyrosine ring-13C6) hydrochloride is the 13C labeled compound of 3,3',5-Triiodothyronine hydrochloride.

5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist that binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).

CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low concentrations.

CCT365623 is an orally bioavailable Lysyl Oxidase inhibitor with good anti-LOX potency, selectivity, pharmacokinetic properties, as well as anti-metastatic efficacy.