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Anti-STAT3 Monoclonal Antibody (6O845)
(Synonyms: STAT3, MGC16063, HIES, FLJ20882, APRF) Copy Product Info
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Synonyms: STAT3, MGC16063, HIES, FLJ20882, APRF
Catalog No. TMAT-1014 Copy Product Info
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Anti-STAT3 Monoclonal Antibody (6O845) is a Mouse antibody targeting STAT3. Anti-STAT3 Monoclonal Antibody (6O845) can be used in WB,IHC,IF.
Anti-STAT3 Monoclonal Antibody
(6O845)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-STAT3 Monoclonal Antibody (6O845) is a Mouse antibody targeting STAT3. Anti-STAT3 Monoclonal Antibody (6O845) can be used in WB,IHC,IF. |
| Synonyms | STAT3, MGC16063, HIES, FLJ20882, APRF |
| Ig Type | IgG1 |
| Clone | 6O845 |
| Reactivity | Human,Mouse,Rat,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/1000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The Stat3 transcription factor is an important signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development . Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding. Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3a (86 kDa) and Stat3 |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human STAT3 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | STAT3 |
| Gene ID | |
| Protein Name | Signal transducer and activator of transcription 3 |
| Uniprot ID |
| Molecular Weight | Theoretical: 88 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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