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Anti-NOTCH4 Monoclonal Antibody (4O695)

(Synonyms: INT3) Copy Product Info
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Synonyms: INT3

Catalog No. TMAT-1500 Copy Product Info
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Anti-NOTCH4 Monoclonal Antibody (4O695) is a Mouse antibody targeting NOTCH4. Anti-NOTCH4 Monoclonal Antibody (4O695) can be used in IHC,FCM.

Anti-NOTCH4 Monoclonal Antibody
(4O695)

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Product Introduction

Bioactivity
Description
Anti-NOTCH4 Monoclonal Antibody (4O695) is a Mouse antibody targeting NOTCH4. Anti-NOTCH4 Monoclonal Antibody (4O695) can be used in IHC,FCM.
SynonymsINT3
Ig Type
IgG2a
Clone
4O695
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human NOTCH4 (AA: extra 118-357) expressed in E. Coli.
Antigen Species
Human
Gene Name
NOTCH4
Gene ID
Protein Name
Neurogenic locus notch homolog protein 4
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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