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Synonyms: VWDP, GPIbalpha, GPIbA, GP1BA, GP1B, DBPLT3, CD42b-alpha, BSS, BDPLT3, BDPLT1
Anti-CD42B Monoclonal Antibody
(5Q686)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
| Description | Anti-CD42B Monoclonal Antibody (5Q686) is a Mouse antibody targeting CD42B. Anti-CD42B Monoclonal Antibody (5Q686) can be used in WB,FCM. |
| Synonyms | VWDP, GPIbalpha, GPIbA, GP1BA, GP1B, DBPLT3, CD42b-alpha, BSS, BDPLT3, BDPLT1 |
| Ig Type | IgG1 |
| Clone | 5Q686 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD42B (AA: extra 17-183) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | GP1BA |
| Gene ID | |
| Protein Name | Platelet glycoprotein Ib alpha chain |
| Uniprot ID |
| Molecular Weight | Theoretical: 71.5 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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