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Anti-DNMT3B Monoclonal Antibody (1B244)
(Synonyms: M.HsaIIIB, ICF1, ICF) Copy Product Info
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Synonyms: M.HsaIIIB, ICF1, ICF
Catalog No. TMAT-1603 Copy Product Info
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Anti-DNMT3B Monoclonal Antibody (1B244) is a Mouse antibody targeting DNMT3B. Anti-DNMT3B Monoclonal Antibody (1B244) can be used in IF,FCM.
Anti-DNMT3B Monoclonal Antibody
(1B244)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-DNMT3B Monoclonal Antibody (1B244) is a Mouse antibody targeting DNMT3B. Anti-DNMT3B Monoclonal Antibody (1B244) can be used in IF,FCM. |
| Synonyms | M.HsaIIIB, ICF1, ICF |
| Ig Type | IgG2a |
| Clone | 1B244 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human DNMT3B (AA: 1-150) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | DNMT3B |
| Gene ID | |
| Protein Name | DNA (cytosine-5)-methyltransferase 3B |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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